SCHEMBL30892256

SCHEMBL30892256

O=Cc1c(Cl)ccc(Cl)c1O

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
DPP4 P27487 1/20 0.43
PADI4 Q9UM07 1/20 0.41
ERN1 O75460 8/20 0.40
HSD17B10 Q99714 2/20 0.33
CYP3A4 P08684 1/20 0.33
MAPK1 P28482 1/20 0.33
ALDH5A1 P51649 1/20 0.33
ABAT P80404 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL659499 1.00 ALDH1A1 (0.54) ALDH1A1TDP1MEN1KMT2ADPP4
SCHEMBL30892258 1.00 ALDH1A1 (0.54) ALDH1A1TDP1MEN1KMT2ADPP4
SCHEMBL30498483 0.86 ALDH1A1 (0.44) ALDH1A1TDP1MEN1KMT2ADPP4
SCHEMBL27771948 0.82 ERN1 (0.44) ALDH1A1TDP1MEN1KMT2ADPP4
SCHEMBL22492704 0.82 ERN1 (0.55) ALDH1A1TDP1MEN1KMT2ADPP4
SCHEMBL1678698 0.82 ALDH1A1 (0.41) ALDH1A1TDP1MEN1KMT2ADPP4
SCHEMBL29955992 0.82 ALDH1A1 (0.41) ALDH1A1TDP1MEN1KMT2ADPP4
SCHEMBL25322018 0.82 ALDH1A1 (0.46) ALDH1A1TDP1MEN1KMT2ADPP4
SCHEMBL10209989 0.82 ALDH1A1 (0.46) ALDH1A1TDP1MEN1KMT2ADPP4
SCHEMBL14292712 0.82 ALDH1A1 (0.46) ALDH1A1TDP1MEN1KMT2ADPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112299983-B 3, 6-Dichloro salicylic acid compounds and related methods of synthesis 孟山都技术公司 2024-05-17 CN disclosed