SCHEMBL659499

SCHEMBL659499

O=Cc1c(Cl)ccc(Cl)c1O

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
DPP4 P27487 1/20 0.43
PADI4 Q9UM07 1/20 0.41
ERN1 O75460 8/20 0.40
HSD17B10 Q99714 2/20 0.33
CYP3A4 P08684 1/20 0.33
MAPK1 P28482 1/20 0.33
ALDH5A1 P51649 1/20 0.33
ABAT P80404 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30892256 1.00 ALDH1A1 (0.54) ALDH1A1TDP1MEN1KMT2ADPP4
SCHEMBL30892258 1.00 ALDH1A1 (0.54) ALDH1A1TDP1MEN1KMT2ADPP4
SCHEMBL30498483 0.86 ALDH1A1 (0.44) ALDH1A1TDP1MEN1KMT2ADPP4
SCHEMBL27771948 0.82 ERN1 (0.44) ALDH1A1TDP1MEN1KMT2ADPP4
SCHEMBL22492704 0.82 ERN1 (0.55) ALDH1A1TDP1MEN1KMT2ADPP4
SCHEMBL1678698 0.82 ALDH1A1 (0.41) ALDH1A1TDP1MEN1KMT2ADPP4
SCHEMBL29955992 0.82 ALDH1A1 (0.41) ALDH1A1TDP1MEN1KMT2ADPP4
SCHEMBL25322018 0.82 ALDH1A1 (0.46) ALDH1A1TDP1MEN1KMT2ADPP4
SCHEMBL10209989 0.82 ALDH1A1 (0.46) ALDH1A1TDP1MEN1KMT2ADPP4
SCHEMBL14292712 0.82 ALDH1A1 (0.46) ALDH1A1TDP1MEN1KMT2ADPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104447301-A Method for preparing 2-hydroxyl 3,6-dichlorobenzoic acid UNIV SHANGHAI OCEAN 2015-03-25 CN claimed
CN-112299983-B 3, 6-Dichloro salicylic acid compounds and related methods of synthesis 孟山都技术公司 2024-05-17 CN disclosed
CN-107531648-B Herbicidal compounds 先正达参股股份有限公司 2021-07-13 CN disclosed
CN-112299983-A 3,6-dichlorosalicylic acid compounds and related synthetic methods 孟山都技术公司 2021-02-02 CN disclosed
CN-106659162-B 3,6-dichlorosalicylic acid compounds and related synthetic methods 孟山都技术公司 2020-10-27 CN disclosed
US-10807936-B2 3,6-dichlorosalicylic acid compounds and related synthetic processes MONSANTO TECHNOLOGY LLC (US) 2020-10-20 US disclosed
US-10807936-B2 3,6-dichlorosalicylic acid compounds and related synthetic processes MONSANTO TECHNOLOGY LLC (US) 2020-10-20 US disclosed
US-20200181055-A1 3,6-DICHLOROSALICYLIC ACID COMPOUNDS AND RELATED SYNTHETIC PROCESSES MONSANTO TECHNOLOGY LLC (US) 2020-06-11 US disclosed
US-20200181055-A1 3,6-DICHLOROSALICYLIC ACID COMPOUNDS AND RELATED SYNTHETIC PROCESSES MONSANTO TECHNOLOGY LLC (US) 2020-06-11 US disclosed
EP-3151670-B1 3,6-DICHLOROSALICYLIC ACID COMPOUNDS AND RELATED SYNTHETIC PROCESSES MONSANTO TECHNOLOGY LLC (US) 2019-10-02 EP disclosed
WO-2000023433-A1 SUBSTITUTED BENZOPYRAN ANALOGS FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 2000-04-27 WO disclosed
US-6034256-A CYCLOOXYGEASE INHIBITOR G.D. SEARLE & CO. (US) 2000-03-07 US disclosed
EP-0977748-A1 SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 2000-02-09 EP disclosed
WO-1998047890-A1 SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1998-10-29 WO disclosed
US-5714503-A Compounds and methods for inhibition of HIV and related viruses MEDIVIR AB (SE) 1998-02-03 US disclosed
US-5658907-A THIOUREA VIRICIDES MEDIVIR A/B (SE) 1997-08-19 US disclosed
US-5593993-A VIRICIDES FOR HTLV TREATMENT OF AIDS MEDIVIR AB (SE) 1997-01-14 US disclosed
EP-0540143-A2 Compounds and methods for inhibition of HIV and related viruses Medivir Aktiebolag (SE) 1993-05-05 EP disclosed
WO-1993003022-A1 COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES MEDIVIR AB (SE) 1993-02-18 WO disclosed
US-4680385-A Metal dye complexes containing an azo or azomethine dye and a colorless ligand with the C═N--N═C group CIBA-GEIGY CORPORATION (US) 1987-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10807936-B2 3,6-dichlorosalicylic acid compounds and related synthetic processes DDT, HDHD5, DDC ALDH1A1 323/4885TDP1 1330/4885MEN1 4334/4885
US-20200181055-A1 3,6-DICHLOROSALICYLIC ACID COMPOUNDS AND RELATED SYNTHETIC PROCESSES DDT, HDHD5, DDC ALDH1A1 323/4885TDP1 1330/4885MEN1 4334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.