Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.80 |
| ▸ | POLB | P06746 | 2/20 | 0.80 |
| ▸ | NPC1 | O15118 | 4/20 | 0.72 |
| ▸ | RAB9A | P51151 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 6/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.70 |
| ▸ | USP2 | O75604 | 2/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.70 |
| ▸ | CLK1 | P49759 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | GFER | P55789 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4518527 | 0.89 | MEN1 (1.00) | MEN1KMT2APOLBRAB9AGAA | |
| SCHEMBL23270917 | 0.88 | MEN1 (0.76) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL4515151 | 0.86 | MEN1 (0.85) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL25920958 | 0.84 | MEN1 (0.72) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL8738403 | 0.83 | MEN1 (0.70) | MEN1KMT2APOLBNPC1GAA | |
| SCHEMBL4533989 | 0.83 | MEN1 (0.89) | MEN1KMT2APOLBRAB9AGAA | |
| SCHEMBL25920953 | 0.83 | MEN1 (0.64) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL4524776 | 0.83 | MEN1 (0.83) | MEN1KMT2APOLBRAB9AGAA | |
| SCHEMBL4526537 | 0.82 | MEN1 (0.98) | MEN1KMT2APOLBRAB9AGAA | |
| SCHEMBL29170022 | 0.82 | NPC1 (1.00) | MEN1KMT2APOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4333843-A1 | BITHIAZOL DERATIVES AS INHIBITORS OF LYSYL OXIDASES | University of South Carolina (US) | 2024-03-13 | — | — | EP | disclosed |
| US-20240075015-A1 | Inhibitors of Lysyl Oxidases | UNIVERSITY OF SOUTH CAROLINA | 2024-03-07 | — | — | US | disclosed |
| CN-117545480-A | Dithiazole derivatives as inhibitors of lysyl oxidase | 南卡罗来纳大学 | 2024-02-09 | — | — | CN | disclosed |
| US-11712437-B2 | Inhibitors of lysyl oxidases | UNIVERSITY OF SOUTH CAROLINA (US) | 2023-08-01 | — | — | US | disclosed |
| US-11712437-B2 | Inhibitors of lysyl oxidases | UNIVERSITY OF SOUTH CAROLINA (US) | 2023-08-01 | — | — | US | disclosed |
| US-20220378753-A1 | NOVEL INHIBITORS OF LYSYL OXIDASES | UNIVERSITY OF SOUTH CAROLINA (US) | 2022-12-01 | — | — | US | disclosed |
| WO-2022240476-A1 | BITHIAZOL DERATIVES AS INHIBITORS OF LYSYL OXIDASES | UNIVERSITY OF SOUTH CAROLINA (US) | 2022-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240075015-A1 | Inhibitors of Lysyl Oxidases | LOXL1, LOXL2, LOXL4 | MEN1 4801/4885KMT2A 1235/4885POLB 2469/4885 |
| US-20220378753-A1 | NOVEL INHIBITORS OF LYSYL OXIDASES | LOXL1, LOXL2, LOXL4 | MEN1 4832/4885KMT2A 1441/4885POLB 3076/4885 |
| US-11712437-B2 | Inhibitors of lysyl oxidases | LOXL1, LOXL2, LOXL4 | MEN1 4808/4885KMT2A 1401/4885POLB 2775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.