Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331373 | 0.83 | HTR2A (0.45) | HTR2ATP53HTR1AHTR7HTR6 | |
| SCHEMBL4392149 | 0.81 | TAAR1 (0.50) | HTR2ATP53HTR1AHTR7HTR6 | |
| SCHEMBL18482277 | 0.81 | HTR2A (0.41) | HTR2ATP53HTR1AHTR7HTR6 | |
| SCHEMBL9921231 | 0.79 | KCNH2 (0.45) | HTR2ATP53HTR1AHTR7HTR6 | |
| SCHEMBL16404688 | 0.79 | HTR2A (0.40) | HTR2ATP53HTR1AHTR7HTR6 | |
| SCHEMBL29447991 | 0.79 | HTR2A (0.40) | HTR2ATP53HTR1AHTR7HTR6 | |
| SCHEMBL29434711 | 0.79 | CA2 (0.41) | HTR2ATP53HTR1AHTR7HTR6 | |
| SCHEMBL3126933 | 0.79 | HTR2A (0.40) | HTR2ATP53HTR1AHTR7HTR6 | |
| SCHEMBL2339561 | 0.79 | CA2 (0.41) | HTR2ATP53HTR1AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL16401793 | 0.79 | TAAR1 (0.48) | HTR2ATP53HTR1AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138684-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO , INC. (US) | 2023-07-27 | — | — | WO | disclosed |