Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15352199 | 0.84 | PSEN1 (0.42) | HTR2ATP53HTR1AHTR7HTR6 | |
| SCHEMBL25322706 | 0.83 | HTR2A (0.43) | HTR2ATP53HTR1AHTR7HTR6 | |
| SCHEMBL13908021 | 0.82 | HTR2A (0.41) | HTR2ATP53HTR1AHTR7HTR6 | |
| SCHEMBL140474 | 0.82 | HTR2A (0.45) | HTR2ATP53HTR1AHTR7HTR6 | |
| SCHEMBL4604208 | 0.81 | KMT2A (0.48) | HTR2ATP53HTR1AHTR7HTR6 | |
| SCHEMBL25236513 | 0.79 | HTR2A (0.42) | HTR2ATP53HTR1AHTR7HTR6 | |
| SCHEMBL5330355 | 0.79 | HTR2A (0.42) | HTR2ATP53HTR1AHTR7HTR6 | |
| SCHEMBL19045455 | 0.78 | ERCC1 (0.46) | HTR2ATP53HTR1AHTR7HTR6 | |
| SCHEMBL134961 | 0.77 | TP53 (0.41) | HTR2ATP53HTR1AHTR7HTR6 | |
| SCHEMBL4573498 | 0.77 | LMNA (0.42) | HTR2ATP53HTR1AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192831-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| EP-3953344-A1 | GLP-IR AGONISTS AND USES THEREOF | Qilu Regor Therapeutics Inc. (CN) | 2022-02-16 | — | — | EP | disclosed |
| EP-3883928-A1 | GLP-1R AGONISTS AND USES THEREOF | Qilu Regor Therapeutics Inc. (CN) | 2021-09-29 | — | — | EP | disclosed |
| US-10919874-B2 | Metalloenzyme inhibitor compounds | NQP 1598, LTD. (KY) | 2021-02-16 | — | — | US | disclosed |
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |
| WO-2020207474-A1 | GLP-1R AGONISTS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2020-10-15 | — | — | WO | disclosed |
| US-20190382370-A1 | METALLOENZYME INHIBITOR COMPOUNDS | NQP 1598 LTD (KY) | 2019-12-19 | — | — | US | disclosed |
| US-10370354-B2 | Metalloenzyme inhibitor compounds | NQP 1598, LTD. (KY) | 2019-08-06 | — | — | US | disclosed |
| US-20180222884-A1 | METALLOENZYME INHIBITOR COMPOUNDS | NQP 1598, LTD. (KY) | 2018-08-09 | — | — | US | disclosed |
| EP-3351541-A1 | METALLOENZYME INHIBITOR COMPOUNDS | Viamet Pharmaceuticals (NC), Inc. (US) | 2018-07-25 | — | — | EP | disclosed |
| WO-2007100161-A1 | METHOD FOR PREFERENTIAL PRODUCTION OF GEOMETRIC ISOMERS AND ISOLATION METHOD | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-09-07 | — | — | WO | disclosed |
| US-20070049495-A1 | Ethylene derivatives and pesticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-03-01 | — | — | US | disclosed |
| US-7037880-B2 | Ethylene derivatives and pesticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2006-05-02 | — | — | US | disclosed |
| US-20030216394-A1 | Etylene derivatives and pesticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-11-20 | — | — | US | disclosed |
| EP-1360901-A1 | 2,3-cyclic substituted derivatives of 3-hydroxyacrolein and 3-hydroxyacrylic acid as pesticides | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 2003-11-12 | — | — | EP | disclosed |
| US-RE38188-E1 | Ethylene derivatives and pesticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-0913392-B1 | ETHYLENE DERIVATIVES AND PEST CONTROLLING AGENTS | NISSAN CHEMICAL IND LTD (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-6462049-B1 | LOW TOXICITY AND PERSISTENT INSECTICIDES AND FUNGICIDES; PREVENTING ATTACHMENT OF AQUATIC ORGANISMS; ECOSYSTEM FRIENDLY; NONPOLLUTING | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2002-10-08 | — | — | US | disclosed |
| US-6063734-A | AGRICULTURAL CHEMICALS, AGENTS FOR PREVENTING ATTACHMENT OF AQUATIC ORGANISMS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-05-16 | — | — | US | disclosed |
| EP-0913392-A1 | ETHYLENE DERIVATIVES AND PEST CONTROLLING AGENTS | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1999-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190382370-A1 | METALLOENZYME INHIBITOR COMPOUNDS | MMEL1, GAA, GPX1 | HTR2A 3434/4885TP53 2081/4885HTR1A 3412/4885 |
| US-10919874-B2 | Metalloenzyme inhibitor compounds | MMEL1, GAA, GPX1 | HTR2A 3434/4885TP53 2081/4885HTR1A 3412/4885 |
| US-20030216394-A1 | Etylene derivatives and pesticides containing said derivatives | DDT, ECE1, EBPL | HTR2A 2173/4885TP53 2400/4885HTR1A 1754/4885 |
| US-20070049495-A1 | Ethylene derivatives and pesticides containing said derivatives | DDT, ECE1, EBPL | HTR2A 2900/4885TP53 2206/4885HTR1A 2073/4885 |
| US-10370354-B2 | Metalloenzyme inhibitor compounds | MMEL1, GPX1, MPO | HTR2A 3482/4885TP53 2109/4885HTR1A 3439/4885 |
| US-20180222884-A1 | METALLOENZYME INHIBITOR COMPOUNDS | MMEL1, GPX1, MPO | HTR2A 3482/4885TP53 2109/4885HTR1A 3439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.