Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561629 | 0.81 | CTSK (0.40) | CTSKRAB9ANPC1PIK3CAL3MBTL1 | |
| SCHEMBL222210 | 0.78 | KMT2A (0.42) | CTSKRAB9ANPC1PIK3CAL3MBTL1 | |
| SCHEMBL3766193 | 0.75 | RAB9A (0.48) | CTSKRAB9ANPC1PIK3CAL3MBTL1 | |
| SCHEMBL13170046 | 0.72 | MEN1 (0.46) | CTSKRAB9ANPC1PIK3CAL3MBTL1 | |
| SCHEMBL583550 | 0.71 | DHODH (0.57) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL13850731 | 0.71 | MEN1 (0.43) | CTSKRAB9ANPC1PIK3CAL3MBTL1 | |
| SCHEMBL6360441 | 0.70 | MEN1 (0.44) | CTSKRAB9ANPC1PIK3CAL3MBTL1 | |
| SCHEMBL11373303 | 0.69 | MAPT (0.46) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11375069 | 0.69 | KMT2A (0.52) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL11371586 | 0.69 | LMNA (0.50) | RAB9ANPC1L3MBTL1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004201-A1 | PHOSPHODIESTARASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-01-05 | — | — | US | disclosed |
| EP-2346867-A1 | PHOSPHODIESTARASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010046791-A1 | PHOSPHODIESTARASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2010-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004201-A1 | PHOSPHODIESTARASE INHIBITORS | PDE4A, PDE7A, PDE4B | CTSK 378/4885RAB9A 320/4885NPC1 3969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.