⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25327165 | 0.79 | — | — | |
| SCHEMBL25327168 | 0.79 | — | — | |
| SCHEMBL30530715 | 0.77 | L3MBTL1 (0.33) | — | |
| SCHEMBL25912810 | 0.76 | ALOX5 (0.31) | — | |
| SCHEMBL25912806 | 0.76 | ALOX5 (0.31) | — | |
| SCHEMBL25325127 | 0.76 | ALOX5 (0.31) | — | |
| SCHEMBL25326895 | 0.76 | ALOX5 (0.31) | — | |
| SCHEMBL25328428 | 0.73 | OGA (0.32) | — | |
| SCHEMBL30238674 | 0.72 | MEN1 (0.36) | — | |
| SCHEMBL23243769 | 0.72 | HPGD (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250282749-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2025-09-11 | — | — | US | disclosed |
| EP-4469445-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |