Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25325127 | 1.00 | ALOX5 (0.31) | ALOX5CES2CES1KEAP1SLC7A5 | |
| SCHEMBL25326895 | 1.00 | ALOX5 (0.31) | ALOX5CES2CES1KEAP1SLC7A5 | |
| SCHEMBL30530715 | 0.84 | L3MBTL1 (0.33) | ALOX5L3MBTL1 | |
| SCHEMBL25328396 | 0.81 | MEN1 (0.40) | CES2CES1KEAP1L3MBTL1 | |
| SCHEMBL25326074 | 0.81 | MEN1 (0.40) | CES2CES1KEAP1L3MBTL1 | |
| SCHEMBL30238674 | 0.78 | MEN1 (0.36) | ALOX5L3MBTL1 | |
| SCHEMBL16169010 | 0.77 | MAPT (0.34) | ALOX5 | |
| SCHEMBL23243770 | 0.76 | HPGD (0.41) | L3MBTL1 | |
| SCHEMBL23243769 | 0.76 | HPGD (0.41) | L3MBTL1 | |
| SCHEMBL25326465 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |