(Chloromethyl)Benzene

(Chloromethyl)Benzene

SCHEMBL253266

C=CC(=O)OC(C)(C)CN.ClCc1ccccc1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.40
CYP3A4 P08684 3/20 0.40
ALDH1A1 P00352 2/20 0.40
CYP2C9 P11712 1/20 0.40
THRB P10828 2/20 0.36
HIF1A Q16665 2/20 0.35
CYP1A2 P05177 2/20 0.33
RECQL P46063 1/20 0.33
CYP2D6 P10635 1/20 0.33
PRMT1 Q99873 1/20 0.33
TGM2 P21980 1/20 0.33
PDE6D O43924 1/20 0.33
PPARG P37231 1/20 0.33
PPARA Q07869 1/20 0.33
MAPK1 P28482 1/20 0.33
POLB P06746 1/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 1/20 0.33
CTSK P43235 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Chloromethyl)Benzene SCHEMBL3200943 0.82 CYP2C19 (0.40) CYP2C19CYP3A4ALDH1A1CYP2C9THRB
Chloromethane SCHEMBL252738 0.82 TSHR (0.36) CYP3A4ALDH1A1THRBHIF1AMAPK1
(Chloromethyl)Benzene SCHEMBL252406 0.81 ELANE (0.35) CYP2C19CYP3A4ALDH1A1CYP2C9HIF1A
SCHEMBL4827346 0.80 TSHR (0.38) CYP3A4ALDH1A1THRBHIF1AMAPK1
SCHEMBL3248705 0.79 CYP3A4 (0.54) CYP2C19CYP3A4ALDH1A1CYP2C9THRB
(Chloromethyl)Benzene SCHEMBL3200951 0.78 THRB (0.42) CYP2C19CYP3A4ALDH1A1CYP2C9THRB
(Chloromethyl)Benzene SCHEMBL27533618 0.77 ALDH1A1 (0.44) CYP2C19CYP3A4ALDH1A1CYP2C9THRB
Hydrochloric Acid SCHEMBL327649 0.77 TSHR (0.35) CYP3A4ALDH1A1THRBHIF1AMAPK1
SCHEMBL29023306 0.77 ALDH1A1 (0.44) CYP2C19CYP3A4ALDH1A1CYP2C9THRB
(Chloromethyl)Benzene SCHEMBL27131604 0.75 THRB (0.53) CYP3A4ALDH1A1THRBHIF1ATGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8092854-B2 Method of attaching an antimicrobial cationic polyelectrolyte to the surface of a substrate QUICK-MED TECHNOLOGIES, INC. (US) 2012-01-10 US disclosed
US-8088400-B2 Disinfectant with quarternary ammonium polymer and copolymers QUICK-MED TECHNOLOGIES, INC. (US) 2012-01-03 US disclosed