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(Chloromethyl)Benzene

(Chloromethyl)Benzene

SCHEMBL252406

C=C(C)C(=O)OC(C)(C)CN.ClCc1ccccc1

nearest known ligand 0.35

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 1/20 0.35
▸ ALDH1A1 P00352 4/20 0.35
▸ CYP2C19 P33261 2/20 0.35
▸ HIF1A Q16665 2/20 0.35
▸ CYP3A4 P08684 3/20 0.33
▸ CYP1A2 P05177 2/20 0.33
▸ RECQL P46063 1/20 0.33
▸ CYP2D6 P10635 1/20 0.33
▸ PRMT1 Q99873 1/20 0.33
▸ SLC7A5 Q01650 1/20 0.33
▸ PPARG P37231 1/20 0.33
▸ PPARA Q07869 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ CA1 P00915 3/20 0.33
▸ CA2 P00918 2/20 0.33
▸ ATM Q13315 1/20 0.32
▸ CA12 O43570 1/20 0.32
▸ CA7 P43166 1/20 0.32
▸ CA14 Q9ULX7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Chloromethyl)Benzene SCHEMBL3201620 0.82 RIPK1 (0.35) ELANEALDH1A1CYP2C19HIF1ACYP1A2
SCHEMBL8084623 0.82 ELANE (0.36) ELANEALDH1A1CYP2C19HIF1APOLB
Chloromethane SCHEMBL253218 0.82 ALDH1A1 (0.39) ALDH1A1
(Chloromethyl)Benzene SCHEMBL253266 0.81 CYP2C19 (0.40) ALDH1A1CYP2C19HIF1ACYP3A4CYP1A2
SCHEMBL735183 0.80 ALDH1A1 (0.41) ALDH1A1
SCHEMBL5531274 0.79 CTSK (0.44) ELANEALDH1A1CYP2C19HIF1ACYP3A4
(Chloromethyl)Benzene SCHEMBL3201628 0.78 ALDH1A1 (0.38) ELANEALDH1A1HIF1ARECQLPPARG
(Chloromethyl)Benzene SCHEMBL28290709 0.77 ALDH1A1 (0.52) ELANEALDH1A1CYP2C19CYP3A4CYP2D6
Hydrochloric Acid SCHEMBL327263 0.77 ALDH1A1 (0.38) ALDH1A1
(Chloromethyl)Benzene SCHEMBL27616626 0.75 TDP1 (0.46) ALDH1A1HIF1ARECQLSLC7A5CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011103158-A1 SYSTEMS AND METHODS THAT KILL INFECTIOUS AGENTS (BACTERIA) WITHOUT THE USE OF A SYSTEMIC ANTI-BIOTIC BLACK MICHAEL DARRYL (US) 2011-08-25 — — WO claimed
US-20110200655-A1 Systems and methods that kill infectious agents (bacteria) without the use of a systemic anti-biotic BLACK MICHAEL DARRYL 2011-08-18 — — US claimed
EP-1450966-A4 ABSORBENT MATERIALS WITH COVALENTLY-BONDED, NONLEACHABLE, POLYMERIC ANTIMICROBIAL SURFACES, AND METHODS FOR PREPARATION QUICK MED TECHNOLOGIES INC (US) 2009-09-09 — — EP claimed
US-20080206293-A1 Absorbent substrate with a non-leaching antimicrobial activity and a controlled-release bioactive agent. QUICK-MED TECHNOLOGIES, INC. (US) 2008-08-28 — — US claimed
US-20050033251-A1 Microbiocides; coating to gauze -type wound dressing QUICK-MED TECHNOLOGIES, INC. (US) 2005-02-10 — — US claimed
EP-1450966-A2 ABSORBENT MATERIALS WITH COVALENTLY-BONDED, NONLEACHABLE, POLYMERIC ANTIMICROBIAL SURFACES, AND METHODS FOR PREPARATION Quick Med Technologies, Inc. (US) 2004-09-01 — — EP claimed
WO-2003039602-A2 ABSORBENT MATERIALS WITH COVALENTLY-BONDED, NONLEACHABLE, POLYMERIC ANTIMICROBIAL SURFACES, AND METHODS FOR PREPARATION QUICK MED TECHNOLOGIES, INC. (US) 2003-05-15 — — WO claimed
US-20020177828-A1 Absorbent materials with covalently-bonded, nonleachable, polymeric antimicrobial surfaces, and methods for preparation PHRONESIS PARTNERS, L.P. 2002-11-28 — — US claimed
US-8092854-B2 Method of attaching an antimicrobial cationic polyelectrolyte to the surface of a substrate QUICK-MED TECHNOLOGIES, INC. (US) 2012-01-10 — — US disclosed
US-8088400-B2 Disinfectant with quarternary ammonium polymer and copolymers QUICK-MED TECHNOLOGIES, INC. (US) 2012-01-03 — — US disclosed