Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 7/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2528887 | 0.88 | MEN1 (0.34) | MEN1KMT2AAAK1PDK2 | |
| SCHEMBL2528533 | 0.87 | F2 (0.39) | MEN1KMT2APDK2 | |
| SCHEMBL2525221 | 0.86 | LMNA (0.38) | MEN1KMT2AAAK1 | |
| SCHEMBL2531550 | 0.85 | KMT2A (0.35) | PTPN1MEN1KMT2ADDR1AAK1 | |
| SCHEMBL2532856 | 0.85 | MEN1 (0.36) | ALPLMEN1KMT2AAAK1 | |
| SCHEMBL2530437 | 0.84 | TSHR (0.39) | MEN1KMT2AAAK1WDR5 | |
| SCHEMBL2532684 | 0.82 | PTPN1 (0.41) | PTPN1ALPLPPARGDDR1ADRA2A | |
| SCHEMBL2526994 | 0.82 | P2RX7 (0.41) | MEN1KMT2A | |
| SCHEMBL2526637 | 0.82 | P2RX7 (0.40) | PPARGMEN1KMT2A | |
| SCHEMBL2530985 | 0.81 | AOC3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | disclosed |
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | HRH1, HRH3, HRH2 | PTPN1 4450/4885ALPL 4554/4885PPARG 1096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.