Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26106679 | 1.00 | — | — | |
| SCHEMBL3873438 | 1.00 | LMNA (0.41) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL3879426 | 1.00 | LMNA (0.41) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL8172735 | 1.00 | LMNA (0.41) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL96682 | 0.97 | — | — | |
| SCHEMBL4910631 | 0.88 | — | — | |
| SCHEMBL28927420 | 0.79 | LMNA (0.38) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL3416469 | 0.79 | TRPV1 (0.48) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL19783667 | 0.78 | TRPV1 (0.46) | LMNAALDH1A1TSHRTRPV1TRPA1 | |
| SCHEMBL3778363 | 0.77 | LMNA (0.50) | LMNAALDH1A1TSHRHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2661502-B1 | BIOSENSOR FOR DETECTING THE PRESENCE OF PROTEASES AND OPTIONALLY QUANTIFYING THE ENZYMATIC ACTIVITY THEREOF | Commissariat à l'énergie atomique et aux énergies alternatives (FR) | 2016-03-09 | — | — | EP | disclosed |
| EP-2661502-A1 | BIOSENSOR FOR DETECTING THE PRESENCE OF PROTEASES AND OPTIONALLY QUANTIFYING THE ENZYMATIC ACTIVITY THEREOF | Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) | 2013-11-13 | — | — | EP | disclosed |
| WO-2012093162-A1 | BIOSENSOR FOR DETECTING THE PRESENCE OF PROTEASES AND OPTIONALLY QUANTIFYING THE ENZYMATIC ACTIVITY THEREOF | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2012-07-12 | — | — | WO | disclosed |
| US-20110256552-A1 | METHOD FOR PREPARING A SUBSTRATE FOR IMMOBILIZING A CELL, SAID SUBSTRATE AND USES THEREOF | UNIVERSITE VICTOR SEGALEN BORDEAUX 2 (FR) | 2011-10-20 | — | — | US | disclosed |
| WO-2010000593-A1 | BIOCHIPS FOR DETECTING THE ENZYMATIC ACTIVITY OF A PROTEASE ENZYME | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2010-01-07 | — | — | WO | disclosed |
| EP-2139999-A1 | METHOD FOR PREPARING A SUBSTRATE FOR IMMOBILISING A CELL, SAID SUBSTRATE AND USES THEREOF | Université Victor Segalen Bordeaux 2 (FR) | 2010-01-06 | — | — | EP | disclosed |
| US-7491745-B2 | Pyrrole-Type compounds, compositions and methods for treating cancer or viral disease | GEMIN X PHARMACEUTICALS CANADA INC. (CA) | 2009-02-17 | — | — | US | disclosed |
| WO-2008125637-A1 | METHOD FOR PREPARING A SUBSTRATE FOR IMMOBILISING A CELL, SAID SUBSTRATE AND USES THEREOF | UNIVERSITE VICTOR SEGALEN - BORDEAUX 2 (FR) | 2008-10-23 | — | — | WO | disclosed |
| US-20070037856-A1 | e.g. 2-Ethyl-11-((3-methoxy-5-(1H-pyrrol-2-yl)-2H-pyrrol-2-ylidene)methyl)-10-azabicyclo[7.2.1]dodeca-9(12),11-diene; anticarcinogenic agent; antiproliferative agent, viricide | GEMIN X BIOTECHNOLOGIES INC. (CA) | 2007-02-15 | — | — | US | disclosed |
| EP-1431286-A2 | Prodigiosin derivatives for treating cancer or viral diseases | Gemin X Biotechnologies Inc. (CA) | 2004-06-23 | — | — | EP | disclosed |
| US-20030009032-A1 | Pyrrole-type compounds, compositions, and methods for treating cancer or viral diseases | GEMIN X PHARMACEUTICALS CANADA INC. (CA) | 2003-01-09 | — | — | US | disclosed |
| EP-1255753-A2 | PRODIGIOSIN-DERIVATIVES AS NEOPLASTIC AND ANTI-VIRAL AGENTS | Gemin X Biotechnologies Inc. (CA) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001055131-A2 | PRODIGIOSIN-DERIVATIVES AS NEOPLASTIC AND ANTI-VIRAL AGENTS | GEMIN X BIOTECHNOLOGIES INC. (CA) | 2001-08-02 | — | — | WO | disclosed |
| US-5620677-A | CONTRAST AGENTS IN DIAGNOSTIC RADIOLOGY | STERLING WINTHROP INC. (US) | 1997-04-15 | — | — | US | disclosed |
| US-5607660-A | X-RAY CONTRAST AGENTS FOR INTESTINES | STERLING WINTHROP INC. (US) | 1997-03-04 | — | — | US | disclosed |
| US-5531979-A | X-RAY CONTRAST COMPOSITION | STERLING WINTHROP INC. (US) | 1996-07-02 | — | — | US | disclosed |
| EP-0609586-A2 | Compositions of iodophenoxy alkanes and iodophenyl ethers for visualization of the gastrointestinal tract | NYCOMED IMAGING AS (NO) | 1994-08-10 | — | — | EP | disclosed |
| EP-0609587-A2 | Compositions of iodophenoxy alkanes and iodophenyl ethers in film-forming materials for visualization of the gastrointestinal tract | NYCOMED IMAGING AS (NO) | 1994-08-10 | — | — | EP | disclosed |
| US-5326553-A | Compositions of iodophenoxy alkanes and iodophenyl ethers in film-forming materials for visualization of the gastrointestinal tract | STERLING WINTHROP INC. (US) | 1994-07-05 | — | — | US | disclosed |
| US-5316755-A | AQUEOUS X-RAY CONTRAST COMPOSITION FOR ORAL OR RECTAL ADMINISTRATION | STERLING WINTHROP INC. (US) | 1994-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030009032-A1 | Pyrrole-type compounds, compositions, and methods for treating cancer or viral diseases | POLI, PYCR1, ZC3HAV1 | LMNA 3539/4885ALDH1A1 3326/4885TSHR 4715/4885 |
| US-20070037856-A1 | e.g. 2-Ethyl-11-((3-methoxy-5-(1H-pyrrol-2-yl)-2H-pyrrol-2-ylidene)methyl)-10-azabicyclo[7.2.1]dodeca-9(12),11-diene; anticarcinogenic agent; antiproliferative agent, viricide | POLI, PCNA, ELL | LMNA 2969/4885ALDH1A1 2915/4885TSHR 4562/4885 |
| US-20110256552-A1 | METHOD FOR PREPARING A SUBSTRATE FOR IMMOBILIZING A CELL, SAID SUBSTRATE AND USES THEREOF | FUS, NEFM, PIGS | LMNA 484/4885ALDH1A1 1910/4885TSHR 3241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.