Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25325850 | 0.98 | MGLL (0.44) | MGLLCA12CA1CA9CA2 | |
| Hydrochloric Acid SCHEMBL25324285 | 0.92 | CA12 (0.44) | MGLLCA12CA1CA9CA2 | |
| SCHEMBL5485564 | 0.90 | CA12 (0.45) | MGLLCA12CA1CA9CA2 | |
| Hydrochloric Acid SCHEMBL25405995 | 0.84 | CA12 (0.36) | CA12CA1CA9CA2TSHR | |
| Hydrochloric Acid SCHEMBL261161 | 0.81 | EHMT2 (0.33) | MGLLCA12CA1CA9CA2 | |
| Hydrochloric Acid SCHEMBL14862018 | 0.78 | CA12 (0.44) | MGLLCA12CA1CA9CA2 | |
| Hydrochloric Acid SCHEMBL25405687 | 0.78 | CA12 (0.42) | MGLLCA12CA1CA9CA2 | |
| SCHEMBL1119578 | 0.78 | EHMT2 (0.35) | MGLLCA12CA1CA9CA2 | |
| SCHEMBL7792536 | 0.78 | CA12 (0.47) | MGLLCA12CA1CA9CA2 | |
| Hydrochloric Acid SCHEMBL8717384 | 0.77 | CA12 (0.41) | MGLLCA12CA1CA9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265113-A1 | PROCESS FOR PREPARING POLYSULFANE SILANES BY MEANS OF PHASE TRANSFER CATALYSIS | EVONIK OPERATIONS GMBH (DE) | 2023-08-24 | — | — | US | claimed |
| EP-4208469-A1 | PROCESS FOR PREPARING POLYSULFANE SILANES BY MEANS OF PHASE TRANSFER CATALYSIS | Evonik Operations GmbH (DE) | 2023-07-12 | — | — | EP | claimed |
| CN-114195819-A | Method for preparing polysulfanylsilanes by phase transfer catalysis | 赢创运营有限公司 | 2022-03-18 | — | — | CN | claimed |
| WO-2022048914-A1 | PROCESS FOR PREPARING POLYSULFANE SILANES BY MEANS OF PHASE TRANSFER CATALYSIS | EVONIK OPERATIONS GMBH (DE) | 2022-03-10 | — | — | WO | claimed |
| US-20230265113-A1 | PROCESS FOR PREPARING POLYSULFANE SILANES BY MEANS OF PHASE TRANSFER CATALYSIS | EVONIK OPERATIONS GMBH (DE) | 2023-08-24 | — | — | US | disclosed |
| CN-114195819-A | Method for preparing polysulfanylsilanes by phase transfer catalysis | 赢创运营有限公司 | 2022-03-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265113-A1 | PROCESS FOR PREPARING POLYSULFANE SILANES BY MEANS OF PHASE TRANSFER CATALYSIS | MRPS22, MRPS23, SRM | MGLL 3134/4885CA12 1733/4885CA1 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.