Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.36 |
| ▸ | FABP7 | O15540 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30522964 | 1.00 | TACR1 (0.38) | TACR1RIPK1PDK1PDK2PDK3 | |
| SCHEMBL25326993 | 0.95 | RIPK1 (0.39) | TACR1RIPK1PDK1PDK2PDK3 | |
| SCHEMBL25326997 | 0.95 | RIPK1 (0.39) | TACR1RIPK1PDK1PDK2PDK3 | |
| SCHEMBL30523018 | 0.90 | PDK1 (0.37) | TACR1RIPK1PDK1PDK2PDK3 | |
| SCHEMBL25327440 | 0.88 | RIPK1 (0.33) | TACR1RIPK1PDK1PDK2PDK3 | |
| SCHEMBL25326008 | 0.86 | RIPK1 (0.42) | RIPK1PDK1PDK2PDK3PDK4 | |
| SCHEMBL25326010 | 0.86 | RIPK1 (0.42) | RIPK1PDK1PDK2PDK3PDK4 | |
| SCHEMBL25328181 | 0.85 | TACR1 (0.37) | TACR1RIPK1PDK1PDK2PDK3 | |
| SCHEMBL30523039 | 0.85 | TACR1 (0.37) | TACR1RIPK1PDK1PDK2PDK3 | |
| SCHEMBL25326570 | 0.85 | PDK1 (0.40) | TACR1RIPK1PDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |