Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 5/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25327480 | 1.00 | RIPK1 (0.42) | RIPK1HRH3ALDH1A1GLAHPGD | |
| SCHEMBL25326948 | 0.94 | RIPK1 (0.42) | RIPK1HRH3 | |
| SCHEMBL25326953 | 0.94 | RIPK1 (0.42) | RIPK1HRH3 | |
| SCHEMBL25328455 | 0.87 | PRMT5 (0.40) | RIPK1HRH3ALDH1A1GLAHPGD | |
| SCHEMBL25328458 | 0.87 | PRMT5 (0.40) | RIPK1HRH3ALDH1A1GLAHPGD | |
| SCHEMBL25326937 | 0.84 | NR1H2 (0.45) | RIPK1 | |
| SCHEMBL25326942 | 0.84 | NR1H2 (0.45) | RIPK1 | |
| SCHEMBL25327731 | 0.81 | PRMT5 (0.41) | RIPK1HRH3 | |
| SCHEMBL25327730 | 0.81 | PRMT5 (0.41) | RIPK1HRH3 | |
| SCHEMBL25328385 | 0.77 | POLB (0.50) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |