Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19611882 | 0.92 | — | — | |
| SCHEMBL28824126 | 0.83 | EPHX1 (0.46) | CNR2FAAH | |
| SCHEMBL14378864 | 0.81 | PAOX (0.46) | TDP1 | |
| Ammonia Solution, Strong SCHEMBL28111373 | 0.81 | EPHX1 (0.44) | CNR2FAAH | |
| SCHEMBL28184077 | 0.81 | PAOX (0.46) | TDP1 | |
| SCHEMBL27856421 | 0.79 | TDP1 (0.39) | TDP1CNR2 | |
| SCHEMBL28132626 | 0.74 | GRM4 (0.31) | — | |
| SCHEMBL28251787 | 0.74 | KISS1R (0.36) | — | |
| SCHEMBL27546682 | 0.74 | KDM4C (0.35) | TDP1CNR2 | |
| SCHEMBL27541532 | 0.74 | CNR2 (0.38) | TDP1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143482-A1 | 2-AMINOPYRIMIDINE COMPOUND OR SALT, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海辉启生物医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |