Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 6/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27541532 | 0.87 | CNR2 (0.38) | TDP1CNR2PRKCACNR1ELANE | |
| Ammonia Solution, Strong SCHEMBL28029565 | 0.85 | CNR2 (0.37) | TDP1CNR2PRKCACNR1 | |
| SCHEMBL19611882 | 0.82 | — | — | |
| SCHEMBL28824126 | 0.80 | EPHX1 (0.46) | CNR2 | |
| SCHEMBL25328102 | 0.79 | TDP1 (0.33) | TDP1CNR2 | |
| SCHEMBL14378864 | 0.79 | PAOX (0.46) | TDP1 | |
| Ammonia Solution, Strong SCHEMBL28111373 | 0.79 | EPHX1 (0.44) | CNR2 | |
| SCHEMBL28184077 | 0.79 | PAOX (0.46) | TDP1 | |
| SCHEMBL28132626 | 0.79 | GRM4 (0.31) | — | |
| SCHEMBL28251787 | 0.79 | KISS1R (0.36) | PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102924390-B | Synthetic method of 1,5-diazacyclooctane-1-tert-butyl ester formate | SUZHOU KANGRUN PHARMACEUTICALS INC | 2014-12-31 | — | — | CN | claimed |
| CN-106967066-B | Novel ss-lactam enzyme inhibitor and preparation method thereof | 明治制果药业株式会社 | 2019-07-30 | — | — | CN | disclosed |
| CN-105859609-B | Beta-lactamase inhibitor and preparation method thereof | 明治制果药业株式会社 | 2019-04-09 | — | — | CN | disclosed |
| CN-108727407-A | Novel benzodiazepine * derivatives | 伊缪诺金公司 | 2018-11-02 | — | — | CN | disclosed |
| CN-108295073-A | Multi-fluorinated compounds are as bruton's tyrosine kinase inhibitor | 浙江导明医药科技有限公司 | 2018-07-20 | — | — | CN | disclosed |
| CN-106061976-B | Polyfluoro compounds as bruton's tyrosine kinase inhibitors | 浙江导明医药科技有限公司 | 2018-05-15 | — | — | CN | disclosed |
| CN-106967066-A | New beta lactamase restrainer and preparation method thereof | 明治制果药业株式会社 | 2017-07-21 | — | — | CN | disclosed |
| CN-104910148-B | Aminotriazole(ATA) and pyridine and its as kinase inhibitor purposes | 西格诺药品有限公司 | 2017-06-27 | — | — | CN | disclosed |
| CN-106661084-A | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-104334559-B | Beta-lactamase inhibitor and preparation method thereof | 明治制果药业株式会社 | 2017-03-22 | — | — | CN | disclosed |
| CN-102971325-B | For reducing the compound that amyloid-beta produces | BRISTOL-MYERS SQUIBB CO. (US) | 2016-01-20 | — | — | CN | disclosed |
| CN-105198908-A | Novel benzodiazepine derivatives | IMMUNOGEN INC | 2015-12-30 | — | — | CN | disclosed |
| CN-105175434-A | NOVEL BENZODIAZEPINE DERIVATIVES | IMMUNOGEN INC | 2015-12-23 | — | — | CN | disclosed |
| CN-105017256-A | Polyfluorinated compound Bruton tyrosine kinase inhibitor | ZHEJIANG DAOMING PHARMACEUTICAL CO LTD | 2015-11-04 | — | — | CN | disclosed |
| CN-104910148-A | Aminotriazolopyridines and use thereof as kinase inhibitors | SIGNAL PHARM LLC | 2015-09-16 | — | — | CN | disclosed |
| CN-102365021-B | Novel benzodiazepine derivatives | IMMUNOGEN INC | 2015-07-15 | — | — | CN | disclosed |
| CN-102203093-B | Aminotriazolopyridines and their use as kinase inhibitors | SIGNAL PHARM LLC | 2015-05-13 | — | — | CN | disclosed |
| CN-104334559-A | Novel beta-lactamase inhibitor and process for preparing the same | MEIJI SEIKA PHARMA CO LTD | 2015-02-04 | — | — | CN | disclosed |
| CN-102924390-B | Synthetic method of 1,5-diazacyclooctane-1-tert-butyl ester formate | SUZHOU KANGRUN PHARMACEUTICALS INC | 2014-12-31 | — | — | CN | disclosed |
| CN-102365021-A | Novel benzodiazepine derivatives | IMMUNOGEN INC | 2012-02-29 | — | — | CN | disclosed |