Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MMP2 | P08253 | 3/20 | 0.54 |
| ▸ | MMP8 | P22894 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ATP4A | P20648 | 1/20 | 0.49 |
| ▸ | ATP4B | P51164 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25328345 | 0.94 | MMP2 (0.54) | MAPTALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL28911459 | 0.87 | MAPT (0.55) | MAPTALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL30118314 | 0.87 | MAPT (0.55) | MAPTALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL25329191 | 0.87 | RAB9A (0.59) | MAPTALDH1A1HSD17B10LMNAMMP2 | |
| SCHEMBL25916900 | 0.84 | RAB9A (0.54) | MAPTALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL25917129 | 0.82 | KMT2A (0.53) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL25916891 | 0.80 | RAB9A (0.55) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL12297713 | 0.78 | RAB9A (0.75) | MAPTALDH1A1HSD17B10LMNAMEN1 | |
| SCHEMBL25917077 | 0.78 | MAPT (0.47) | MAPTALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL25917143 | 0.78 | RAB9A (0.48) | MAPTALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141262-A1 | BAX ACTIVATORS AND USE THEREOF | IPSEN PHARMA S.A.S. (FR) | 2023-07-27 | — | — | WO | disclosed |