Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | LDHA | P00338 | 4/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25916891 | 0.93 | RAB9A (0.55) | RAB9ANPC1LDHAMAPTSIRT5 | |
| SCHEMBL25917116 | 0.86 | RAB9A (0.48) | RAB9ANPC1LDHAMAPTSIRT5 | |
| SCHEMBL25329191 | 0.84 | RAB9A (0.59) | RAB9ANPC1LDHAMAPTALDH1A1 | |
| SCHEMBL25328215 | 0.84 | MAPT (0.54) | RAB9ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL25917257 | 0.83 | SIRT5 (0.55) | RAB9ANPC1MAPTSIRT5ALDH1A1 | |
| SCHEMBL25917200 | 0.83 | SIRT5 (0.55) | RAB9ANPC1LDHAMAPTSIRT5 | |
| SCHEMBL25917143 | 0.81 | RAB9A (0.48) | RAB9ANPC1LDHAMAPTALDH1A1 | |
| SCHEMBL25328345 | 0.78 | MMP2 (0.54) | RAB9ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL25917129 | 0.77 | KMT2A (0.53) | RAB9ANPC1LDHAMAPTSIRT5 | |
| SCHEMBL17900244 | 0.76 | LDHA (0.75) | LDHAALDH1A1POLBKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141262-A1 | BAX ACTIVATORS AND USE THEREOF | IPSEN PHARMA S.A.S. (FR) | 2023-07-27 | — | — | WO | disclosed |