Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL25326522 | 0.94 | OPRM1 (0.38) | OPRM1OPRD1OPRK1POLBALOX5 | |
| SCHEMBL14833616 | 0.89 | POLB (0.49) | OPRM1OPRD1OPRK1POLBALOX5 | |
| SCHEMBL25326429 | 0.87 | SMN1; SMN2 (0.35) | SMN1; SMN2KMT2ASIGMAR1 | |
| SCHEMBL25326553 | 0.85 | RIPK1 (0.41) | OPRM1OPRD1OPRK1POLBALOX5 | |
| SCHEMBL25326913 | 0.85 | RIPK1 (0.50) | OPRM1OPRD1OPRK1RIPK1 | |
| SCHEMBL25326466 | 0.83 | OPRM1 (0.41) | OPRM1OPRD1OPRK1POLBALOX5 | |
| SCHEMBL25326514 | 0.83 | MEN1 (0.36) | OPRM1OPRD1OPRK1POLBALOX5 | |
| SCHEMBL14813848 | 0.82 | RORC (0.42) | MEN1KMT2A | |
| SCHEMBL14813850 | 0.82 | RORC (0.42) | MEN1KMT2A | |
| SCHEMBL14813851 | 0.82 | RORC (0.42) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |