Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 8/20 | 0.68 |
| ▸ | RAB9A | P51151 | 8/20 | 0.68 |
| ▸ | MEN1 | O00255 | 8/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.68 |
| ▸ | NPC1 | O15118 | 6/20 | 0.68 |
| ▸ | GAA | P10253 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.65 |
| ▸ | RELA | Q04206 | 4/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.65 |
| ▸ | VCP | P55072 | 1/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24590341 | 0.85 | PTGS2 (0.72) | PTGS2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL12297852 | 0.83 | PTGS2 (1.00) | PTGS2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL7537503 | 0.83 | PTGS2 (1.00) | PTGS2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL30118253 | 0.82 | NPC1 (0.68) | PTGS2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL28911472 | 0.82 | NPC1 (0.68) | PTGS2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL28030442 | 0.81 | MAPT (0.67) | PTGS2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL24590327 | 0.81 | RAB9A (0.68) | PTGS2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL24590324 | 0.81 | PTGS2 (0.67) | PTGS2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL24590148 | 0.81 | PTGS2 (0.67) | PTGS2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL3595657 | 0.81 | PTGS2 (0.66) | PTGS2MAPTRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141262-A1 | BAX ACTIVATORS AND USE THEREOF | IPSEN PHARMA S.A.S. (FR) | 2023-07-27 | — | — | WO | disclosed |
| WO-2023141262-A1 | BAX ACTIVATORS AND USE THEREOF | IPSEN PHARMA S.A.S. (FR) | 2023-07-27 | — | — | WO | disclosed |
| CN-113880786-B | Synthesis method and anti-oxidation application of camphene aldehyde thiazole hydrazone derivative | 江西农业大学 | 2023-03-03 | — | — | CN | disclosed |
| CN-115448915-A | SIRT5 inhibitor and preparation method and application thereof | 广西师范大学 | 2022-12-09 | — | — | CN | disclosed |