Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5736369 | 0.95 | LMNA (0.43) | ACHELMNADRD3CYP1A2MAOA | |
| SCHEMBL3694813 | 0.88 | CYP2A6 (0.44) | ACHELMNADRD3CYP1A2MAOA | |
| SCHEMBL5543098 | 0.81 | ABL1 (0.45) | ACHELMNADRD3CYP1A2MAOA | |
| SCHEMBL7140128 | 0.80 | BCHE (0.47) | ACHEKDM4ERAB9ABCHEALDH1A1 | |
| SCHEMBL5853542 | 0.79 | ABL1 (0.47) | ACHELMNADRD3CYP1A2MAOA | |
| SCHEMBL5538917 | 0.79 | ABL1 (0.47) | ACHELMNADRD3CYP1A2MAOA | |
| SCHEMBL11074896 | 0.79 | ABL1 (0.47) | ACHELMNADRD3CYP1A2MAOA | |
| SCHEMBL11274621 | 0.79 | ABL1 (0.47) | ACHELMNADRD3CYP1A2MAOA | |
| SCHEMBL11275854 | 0.79 | ABL1 (0.47) | ACHELMNADRD3CYP1A2MAOA | |
| SCHEMBL11279916 | 0.79 | ABL1 (0.47) | ACHELMNADRD3CYP1A2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8038732-B2 | Fluorescent entity, dyeing composition containing at least one fluorescent entity, and method for lightening keratin materials using said at least one fluorescent entity | L'OREAL S.A. (FR) | 2011-10-18 | — | — | US | disclosed |
| US-20100287714-A1 | DYE COMPOSITION CONTAINING A THIOL/DISULPHIDE FLUORESCENT DYE COMPRISING AMINO GROUPS AND COMPRISING AN INTERNAL CATIONIC CHARGE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | L'ORÉAL (FR) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100287714-A1 | DYE COMPOSITION CONTAINING A THIOL/DISULPHIDE FLUORESCENT DYE COMPRISING AMINO GROUPS AND COMPRISING AN INTERNAL CATIONIC CHARGE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | KRT18, DSG1, KRTCAP2 | ACHE 3785/4885LMNA 1650/4885DRD3 3078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.