Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5736369 | 0.85 | LMNA (0.43) | ACHENPC1RAB9AFLT3ALDH1A1 | |
| SCHEMBL5493605 | 0.82 | LMNA (0.43) | ACHERAB9AMAPTALDH1A1ALDH3A1 | |
| SCHEMBL5543098 | 0.81 | ABL1 (0.45) | ACHERAB9AALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL2532889 | 0.80 | ACHE (0.43) | BCHEACHERAB9AFLT3ALDH1A1 | |
| SCHEMBL5538917 | 0.79 | ABL1 (0.47) | BCHEACHEALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL11275854 | 0.79 | ABL1 (0.47) | BCHEACHEALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL2272514 | 0.79 | MEN1 (0.53) | BCHEACHENPC1RAB9AAPAF1 | |
| SCHEMBL5853542 | 0.79 | ABL1 (0.47) | BCHEACHEALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL2447178 | 0.79 | ACHE (0.47) | BCHEACHENPC1RAB9AAPAF1 | |
| SCHEMBL11074896 | 0.79 | ABL1 (0.47) | BCHEACHEALDH1A1ALDH3A1ALDH1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6509365-B1 | 2-phenylbenzimidazoles and 2-phenylindoles, and production and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 2003-01-21 | — | — | US | disclosed |