SCHEMBL25329639

SCHEMBL25329639

CC(=O)Oc1cccc(F)c1F.[Ag]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.47
KDM4E B2RXH2 3/20 0.47
PTGS2 P35354 3/20 0.47
HSD17B10 Q99714 2/20 0.47
ALDH1A1 P00352 2/20 0.47
BLM P54132 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
ESR1 P03372 1/20 0.47
ITGB3 P05106 1/20 0.47
ITGA2B P08514 1/20 0.47
HMGB1 P09429 1/20 0.47
HPGD P15428 1/20 0.47
TSHR P16473 1/20 0.47
GGT1 P19440 1/20 0.47
PTGS1 P23219 1/20 0.47
NAPRT Q6XQN6 1/20 0.47
KMT2A Q03164 3/20 0.46
ACHE P22303 1/20 0.46
CYP4F2 P78329 1/20 0.45
CYP4A11 Q02928 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1700833 0.98 MAPK1 (0.49) MAPK1KDM4EPTGS2HSD17B10ALDH1A1
SCHEMBL31200468 0.98 MAPK1 (0.49) MAPK1KDM4EPTGS2HSD17B10ALDH1A1
SCHEMBL247351 0.82 PTGS2 (0.57) MAPK1KDM4EPTGS2HSD17B10ALDH1A1
SCHEMBL15836535 0.81 KMT2A (0.44) MAPK1ALDH1A1TDP1KMT2ACES2
SCHEMBL868843 0.81 ACHE (0.59) MAPK1KDM4EPTGS2HSD17B10ALDH1A1
SCHEMBL6200625 0.81 MAPK1 (0.47) MAPK1KDM4EPTGS2HSD17B10ALDH1A1
SCHEMBL17355729 0.81 PTPN1 (0.53) MAPK1KDM4EPTGS2HSD17B10ALDH1A1
SCHEMBL28691323 0.81 MAPK1 (0.47) MAPK1KDM4EPTGS2HSD17B10ALDH1A1
SCHEMBL6194083 0.81 MAPK1 (0.47) MAPK1KDM4EPTGS2HSD17B10ALDH1A1
Ammonia Solution, Strong SCHEMBL4479016 0.80 PTGS2 (0.55) MAPK1KDM4EPTGS2HSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2954951-B1 Carrier catalyst and method for producing a porous graphitised carbon material coated with metal nanoparticles HERAEUS DEUTSCHLAND GMBH & CO KG (DE) 2023-08-02 EP disclosed