SCHEMBL25329652

SCHEMBL25329652

Cc1cc(N2CCC(OS(C)(=O)=O)C2=O)cc(C)c1F

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 20/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18740266 0.84 MCHR1 (0.47) MCHR1
SCHEMBL25328999 0.82 CYP2D6 (0.45) MCHR1
SCHEMBL7041206 0.78 HSD11B1 (0.46) MCHR1
SCHEMBL21142409 0.78 MCHR1 (0.42) MCHR1
SCHEMBL8606291 0.78 MCHR1 (0.46) MCHR1
SCHEMBL18740383 0.78 MCHR1 (0.42) MCHR1
SCHEMBL25327268 0.76 CCNA2 (0.37) MCHR1
SCHEMBL18048545 0.76 ROCK2 (0.55) MCHR1
SCHEMBL18048588 0.76 ROCK2 (0.55) MCHR1
SCHEMBL18048615 0.76 ROCK2 (0.55) MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023145769-A1 γ-LACTAM COMPOUND AND COMPOSITION CONTAINING SAME 住友化学株式会社 2023-08-03 WO disclosed