Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5827041 | 0.83 | CA12 (0.53) | MCHR1NOTUM | |
| SCHEMBL8551967 | 0.82 | MCHR1 (0.52) | MCHR1NOTUMROCK2 | |
| SCHEMBL7609602 | 0.82 | MCHR1 (0.52) | MCHR1NOTUMROCK2 | |
| SCHEMBL7610270 | 0.82 | MCHR1 (0.52) | MCHR1NOTUMROCK2 | |
| SCHEMBL18740266 | 0.80 | MCHR1 (0.47) | MCHR1 | |
| SCHEMBL7806269 | 0.79 | SLC6A2 (0.50) | MCHR1 | |
| SCHEMBL25329652 | 0.78 | MCHR1 (0.45) | MCHR1 | |
| SCHEMBL12099243 | 0.77 | HSD11B1 (0.52) | HSD11B1MAOAMAOBKMT2ANOTUM | |
| SCHEMBL18048545 | 0.77 | ROCK2 (0.55) | MCHR1ROCK2 | |
| SCHEMBL18048615 | 0.77 | ROCK2 (0.55) | MCHR1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030171218-A1 | Substituted 3-heteroaryl(amino- or oxy)pyrrolidin-2-ones, their preparation and use as herbicides or plant growth regulators | BAYER CROPSCIENCE GMBH (DE) | 2003-09-11 | — | — | US | disclosed |
| WO-2003005824-A2 | SUBSTITUTED 3-HETEROARYL (AMINO-OR-OXY)-PYRROLIDIN-2-ONES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES OR AS PLANT GROWTH REGULATORS | BAYER CROPSCIENCE GMBH (DE) | 2003-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171218-A1 | Substituted 3-heteroaryl(amino- or oxy)pyrrolidin-2-ones, their preparation and use as herbicides or plant growth regulators | DDT, OXGR1, OGDH | HSD11B1 2424/4885MAOA 1275/4885MAOB 574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.