SCHEMBL25329922

SCHEMBL25329922

CCc1c(C)c(O)cc(C)c1OCC(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN5A Q14524 3/20 0.40
SCN4A P35499 5/20 0.34
CACNA1G O43497 2/20 0.31
CACNA1H O95180 2/20 0.31
CACNA1I Q9P0X4 2/20 0.31
LMNA P02545 2/20 0.31
SCN1A P35498 2/20 0.31
SCN9A Q15858 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
KCNK3 O14649 1/20 0.31
CACNA1F O60840 1/20 0.31
KCNK2 O95069 1/20 0.31
GBA1 P04062 1/20 0.31
MAOA P21397 1/20 0.31
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25329831 0.89 SCN5A (0.37) SCN5ASCN4ALMNASCN1ASCN9A
SCHEMBL25329224 0.87 SCN5A (0.43) SCN5ASCN4ACACNA1GCACNA1HCACNA1I
SCHEMBL25327649 0.86 ALOX15 (0.39) SCN5ACACNA1GCACNA1HCACNA1IALDH1A1
SCHEMBL25328924 0.83 SCN5A (0.47) SCN5ASCN4ALMNASCN1ASCN9A
SCHEMBL25329103 0.83 ALDH1A1 (0.42) SCN5ACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL25328780 0.80 SCN5A (0.32) SCN5ALMNACYP3A4MAPTALDH1A1
SCHEMBL25329419 0.80 PTGS1 (0.36) LMNACYP3A4GLAMAPTKDM4E
SCHEMBL25328769 0.79 ESR1 (0.38) LMNAMAPTKDM4EALDH1A1HPGD
SCHEMBL25328225 0.78 CYP3A4 (0.42) CYP3A4MAPTALDH1A1
SCHEMBL25329828 0.76 SCN5A (0.33) SCN5ACACNA1GCACNA1HCACNA1I

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583813-B2 Polymerization inhibitors BASF SE (DE) 2026-03-24 US disclosed
US-20230242472-A1 POLYMERIZATION INHIBITORS BASF SE (DE) 2023-08-03 US disclosed
EP-4161892-A1 POLYMERIZATION INHIBITORS BASF SE (DE) 2023-04-12 EP disclosed
CN-115697954-A Polymerization inhibitor 巴斯夫欧洲公司 2023-02-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242472-A1 POLYMERIZATION INHIBITORS RCE1, CABLES1, DPYD SCN5A 4507/4885SCN4A 4546/4885CACNA1G 4725/4885
US-12583813-B2 Polymerization inhibitors PTGS1, PTGER1, POT1 SCN5A 4630/4885SCN4A 4023/4885CACNA1G 3847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.