SCHEMBL25329970

SCHEMBL25329970

CCOP(OCC)OCc1ccc(CBr)cc1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.34
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.34
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5953661 0.84 IDO1 (0.47) ALDH1A1
SCHEMBL13053842 0.82 AGXT (0.48) ALDH1A1
SCHEMBL4053548 0.80 APP (0.43) ALDH1A1TSHR
SCHEMBL1450921 0.79 TSHR (0.46) ALDH1A1TSHR
SCHEMBL13863253 0.77 APP (0.49) ALDH1A1TSHR
SCHEMBL7706546 0.77 TRPA1 (0.39) TRPA1ALDH1A1TSHRCYP4F2CYP4A11
SCHEMBL13036816 0.76 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL31124761 0.74 CYP4F2 (0.33) TRPA1ALDH1A1TSHRCYP4F2CYP4A11
SCHEMBL19982577 0.73 TRPA1 (0.36) TRPA1ALDH1A1TSHRCYP4F2CYP4A11
SCHEMBL12646388 0.73 IDO1 (0.54) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118339172-A Phosphonic acid compounds and prodrugs thereof, preparation method and application thereof 上海海和药物研究开发股份有限公司 2024-07-12 CN disclosed
WO-2023138637-A1 PHOSPHONIC ACID COMPOUND AND PRODRUG THEREOF, AND PREPARATION METHODS FOR AND USES OF PHOSPHONIC ACID COMPOUND AND PRODRUG THEREOF 上海海和药物研究开发股份有限公司 2023-07-27 WO disclosed