SCHEMBL4053548

SCHEMBL4053548

CCOP(OCC)OCc1ccc(N)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.43
TSHR P16473 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
CYP3A4 P08684 2/20 0.39
GFER P55789 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAOB P27338 7/20 0.39
LOXL2 Q9Y4K0 1/20 0.38
MAOA P21397 4/20 0.37
MAPT P10636 2/20 0.37
GAA P10253 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP19A1 P11511 2/20 0.35
IDO1 P14902 1/20 0.34
PPIB P23284 1/20 0.34
PPIA P62937 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13659063 0.82 TSHR (0.42) APPTSHRTDP1CYP3A4ALDH1A1
SCHEMBL13053842 0.82 AGXT (0.48) ALDH1A1MAOBMAPTGAARAB9A
SCHEMBL25329970 0.80 TRPA1 (0.34) TSHRALDH1A1
SCHEMBL5953661 0.80 IDO1 (0.47) APPALDH1A1MAOBMAPTIDO1
SCHEMBL1450921 0.79 TSHR (0.46) TSHRTDP1ALDH1A1MAOBMAPT
SCHEMBL13863253 0.77 APP (0.49) APPTSHRTDP1CYP3A4ALDH1A1
SCHEMBL12824780 0.77 TSHR (0.46) APPTSHRTDP1CYP3A4GFER
SCHEMBL28180141 0.76 CYP2A6 (0.52) TSHRALDH1A1MAOBLOXL2MAOA
SCHEMBL13036816 0.76 ALDH1A1 (0.39) TSHRALDH1A1MAPT
SCHEMBL11367135 0.74 TSHR (0.48) APPTSHRTDP1CYP3A4GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572303-B2 A symmetrical dialkyl carbonate, a metal, borong, silicon, or group 7 compound, a hydrogen or hydrocarbon-based fuel, an oxidizer, and a metallic cocatalyst; minimized hydrolysis; improved combustion and storage stability OCTANE INTERNATIONAL, LTD. (US) 2009-08-11 US disclosed
EP-0954558-B1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 2006-06-14 EP disclosed
US-20050044778-A1 Fuel compositions employing catalyst combustion structure OCTANE INTERNATIONAL, LTD. 2005-03-03 US disclosed
US-20040237384-A1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2004-12-02 US disclosed
US-6652608-B1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2003-11-25 US disclosed
EP-1051461-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR, William C. (US) 2000-11-15 EP disclosed
WO-1999066009-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR WILLIAM C (US) 1999-12-23 WO disclosed
EP-0954558-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR, William C. (US) 1999-11-10 EP disclosed
WO-1998026028-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 1998-06-18 WO disclosed