Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 2/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19078350 | 0.82 | STS (0.46) | LGMNGPR119ALDH1A1MEN1KMT2A | |
| SCHEMBL25942333 | 0.82 | LGMN (0.55) | LGMNPDK2MAPTALDH1A1MEN1 | |
| SCHEMBL17305269 | 0.82 | NPSR1 (0.52) | LGMNMAPTALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL25431314 | 0.81 | LGMN (0.54) | LGMNPDK2MAPTALDH1A1MEN1 | |
| SCHEMBL20522647 | 0.81 | ALDH1A1 (0.53) | LGMNMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL20522653 | 0.81 | HPGD (0.48) | ALDH1A1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL19078363 | 0.80 | ALDH1A1 (0.47) | LGMNGPR119MAPTALDH1A1MEN1 | |
| SCHEMBL17305397 | 0.80 | HTT (0.55) | LGMNGPR119MAPTALDH1A1MEN1 | |
| SCHEMBL27359025 | 0.80 | GPR119 (0.55) | GPR119MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL25426990 | 0.80 | LGMN (0.51) | LGMNPDK2MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4466260-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | Astrazeneca AB (SE) | 2024-11-27 | — | — | EP | disclosed |
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |