Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.58 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29742981 | 1.00 | MEN1 (0.61) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Benzoxonium SCHEMBL225516 | 1.00 | MEN1 (0.61) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL10717901 | 1.00 | MEN1 (0.61) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| SCHEMBL27172705 | 0.98 | DNM1 (0.60) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Benzoxonium SCHEMBL3939819 | 0.98 | DNM1 (0.60) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| SCHEMBL27172704 | 0.98 | DNM1 (0.60) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| SCHEMBL11333079 | 0.92 | DNM1 (0.60) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| SCHEMBL28468864 | 0.92 | DNM1 (0.50) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| SCHEMBL28467626 | 0.92 | DNM1 (0.50) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL2059990 | 0.92 | MEN1 (0.71) | MEN1KMT2ATP53SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630663-B2 | Aqueous polyurethane resin dispersion | AGFA NV (BE) | 2026-05-19 | — | — | US | disclosed |
| CN-115667339-B | Aqueous polyurethane resin dispersion | 爱克发有限公司 | 2025-02-25 | — | — | CN | disclosed |
| EP-4165097-B1 | AQUEOUS POLYURETHANE RESIN DISPERSION | AGFA NV (BE) | 2024-03-20 | — | — | EP | disclosed |
| US-20230220145-A1 | Aqueous Polyurethane Resin Dispersion | AGFA NV (BE) | 2023-07-13 | — | — | US | disclosed |
| CN-115667339-A | Aqueous polyurethane resin dispersion | 爱克发有限公司 | 2023-01-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630663-B2 | Aqueous polyurethane resin dispersion | PUF60, PCMT1, EED | MEN1 4498/4885KMT2A 866/4885TP53 1597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.