SCHEMBL25330920

SCHEMBL25330920

O=C(O)[C@]1(CCCCl)C[C@]2(CN1)CC2(F)F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 6/20 0.32
ARG2 P78540 6/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25331176 1.00 ARG1 (0.32) ARG1ARG2
SCHEMBL26964317 0.90
SCHEMBL25330535 0.82
SCHEMBL24649085 0.74
SCHEMBL24649084 0.74
SCHEMBL29974335 0.67 ARG2 (0.49) ARG1ARG2
SCHEMBL29930292 0.67 ARG2 (0.49) ARG1ARG2
SCHEMBL22208186 0.67 ARG2 (0.49) ARG1ARG2
SCHEMBL29977913 0.65 ARG1 (0.36) ARG1ARG2
SCHEMBL26598195 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023138583-A1 HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF 上海湃隆生物科技有限公司 2023-07-27 WO disclosed