SCHEMBL25331007

SCHEMBL25331007

CCCOC(=O)C#CC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.42
LMNA P02545 2/20 0.39
ALDH1A1 P00352 5/20 0.36
ESR1 P03372 1/20 0.34
CHRM1 P11229 1/20 0.34
TSHR P16473 1/20 0.34
SLC6A2 P23975 1/20 0.34
KDR P35968 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PPM1B O75688 1/20 0.33
PTPN1 P18031 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PPP1CC P36873 1/20 0.33
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ATM Q13315 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GLA P06280 1/20 0.31
NAAA Q02083 1/20 0.30
DGKA P23743 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2944738 0.91 HCAR2 (0.43) HCAR2LMNAALDH1A1ESR1CHRM1
SCHEMBL4682515 0.87 ALDH1A1 (0.50) HCAR2LMNAALDH1A1ESR1TSHR
SCHEMBL2941847 0.84 ALDH1A1 (0.46) HCAR2LMNAALDH1A1ESR1CHRM1
SCHEMBL12501914 0.84 NAAA (0.52) HCAR2LMNAALDH1A1TSHRNAAA
SCHEMBL12502101 0.84 NAAA (0.52) HCAR2LMNAALDH1A1TSHRNAAA
SCHEMBL2945975 0.82 HCAR2 (0.38) HCAR2LMNAALDH1A1ESR1CHRM1
SCHEMBL2941839 0.82 ALDH1A1 (0.54) HCAR2LMNAALDH1A1ESR1TSHR
SCHEMBL1857628 0.81 ALDH1A1 (0.43) HCAR2LMNAALDH1A1TSHRHSD17B10
SCHEMBL2945350 0.81 HCAR2 (0.40) HCAR2LMNAALDH1A1ESR1CHRM1
SCHEMBL2947560 0.80 NAAA (0.52) HCAR2LMNAALDH1A1TSHRATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024070622-A1 CARBOXYL GROUP-CONTAINING ACRYLIC RUBBER COMPOSITION AND CROSSLINKED PRODUCT THEREOF 株式会社大阪ソーダ 2024-04-04 WO disclosed
EP-4223511-A1 CARBOXYL GROUP-CONTAINING ACRYLIC RUBBER COMPOSITION AND MULTILAYER BODY Osaka Soda Co., Ltd. (JP) 2023-08-09 EP disclosed
CN-116056886-A Carboxyl group-containing acrylic rubber composition and laminate 株式会社大阪曹达 2023-05-02 CN disclosed
WO-2022071217-A1 CARBOXYL GROUP-CONTAINING ACRYLIC RUBBER COMPOSITION AND MULTILAYER BODY 株式会社大阪ソーダ 2022-04-07 WO disclosed