Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.62 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.56 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.56 |
| ▸ | AHR | P35869 | 2/20 | 0.56 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.56 |
| ▸ | VDR | P11473 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30423164 | 1.00 | CLK4 (0.62) | CLK4DYRK1ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28315176 | 0.87 | CYP1A2 (0.67) | CLK4DYRK1ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29712524 | 0.87 | CYP1A2 (0.67) | CLK4DYRK1ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23383679 | 0.87 | CLK4 (0.65) | CLK4DYRK1ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2876289 | 0.83 | XDH (0.64) | CLK4DYRK1ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28029282 | 0.83 | CLK4 (0.65) | CLK4DYRK1ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4126244 | 0.80 | CLK4 (0.61) | CLK4DYRK1ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29915339 | 0.80 | DYRK1A (0.61) | CLK4DYRK1ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1592678 | 0.80 | CLK4 (0.61) | CLK4DYRK1ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28338207 | 0.80 | CLK4 (0.61) | CLK4DYRK1ACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230247997-A1 | NEMATICIDE COMPOUNDS, COMPOSITIONS, AND METHODS OF THEIR MAKING AND USE | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230247997-A1 | NEMATICIDE COMPOUNDS, COMPOSITIONS, AND METHODS OF THEIR MAKING AND USE | ACHE, NISCH, CASP7 | CLK4 4794/4885DYRK1A 4685/4885CYP1A2 265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.