Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.43 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11848693 | 0.96 | CYP1A2 (0.40) | PDE3BPDE3APDK2LMNAGAA | |
| SCHEMBL10067075 | 0.88 | PDE3B (0.35) | PDE3BPDE3APDK2THRATHRB | |
| SCHEMBL11291373 | 0.84 | MAPT (0.41) | PDK2TSHRLMNANPC1TP53 | |
| SCHEMBL662124 | 0.83 | PDK2 (0.47) | PDE3BPDE3APDK2 | |
| SCHEMBL660896 | 0.83 | PDK2 (0.52) | PDE3BPDE3APDK2 | |
| SCHEMBL19116818 | 0.82 | NCF1 (0.45) | PDE3BPDE3ATSHRTHRA | |
| SCHEMBL10035868 | 0.80 | PDK2 (0.38) | PDE3BPDE3APDK2LMNATP53 | |
| SCHEMBL12200646 | 0.80 | PDK2 (0.33) | PDE3BPDE3APDK2THRATHRB | |
| SCHEMBL25337063 | 0.80 | MAOA (0.39) | — | |
| Bromide SCHEMBL11866816 | 0.74 | EHMT2 (0.51) | PDE3BPDE3ALMNANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250126-A1 | Indodicarbocyanine Phosphoramidites with Bathochromically Shifted Absorption and Emission, and Tunable Hydrophobicity | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250126-A1 | Indodicarbocyanine Phosphoramidites with Bathochromically Shifted Absorption and Emission, and Tunable Hydrophobicity | NT5C3B, PCNA, POLL | PDE3B 2411/4885PDE3A 2166/4885PDK2 3163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.