Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 7/20 | 0.75 |
| ▸ | BCR | P11274 | 7/20 | 0.75 |
| ▸ | PRKCA | P17252 | 3/20 | 0.75 |
| ▸ | CAMK2D | Q13557 | 5/20 | 0.67 |
| ▸ | SRC | P12931 | 5/20 | 0.65 |
| ▸ | PLK1 | P53350 | 1/20 | 0.65 |
| ▸ | EGFR | P00533 | 1/20 | 0.65 |
| ▸ | PRKACA | P17612 | 1/20 | 0.65 |
| ▸ | PRKACG | P22612 | 1/20 | 0.65 |
| ▸ | PRKACB | P22694 | 1/20 | 0.65 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.65 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.65 |
| ▸ | GSK3B | P49841 | 2/20 | 0.65 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | SYK | P43405 | 1/20 | 0.59 |
| ▸ | IKBKB | O14920 | 1/20 | 0.59 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31118910 | 1.00 | ABL1 (0.75) | ABL1BCRPRKCACAMK2DSRC | |
| SCHEMBL31119008 | 0.89 | PLK1 (0.74) | ABL1BCRPRKCACAMK2DSRC | |
| SCHEMBL25337710 | 0.89 | PLK1 (0.74) | ABL1BCRPRKCACAMK2DSRC | |
| SCHEMBL5379812 | 0.88 | ABL1 (0.77) | ABL1BCRPRKCACAMK2DSRC | |
| SCHEMBL3012944 | 0.87 | ABL1 (0.70) | ABL1BCRPRKCACAMK2DSRC | |
| SCHEMBL823915 | 0.86 | CAMK2D (0.82) | ABL1BCRPRKCACAMK2DSRC | |
| SCHEMBL27115954 | 0.86 | ABL1 (0.74) | ABL1BCRPRKCACAMK2DSRC | |
| SCHEMBL1655099 | 0.86 | ABL1 (1.00) | ABL1BCRPRKCACAMK2DSRC | |
| SCHEMBL27444270 | 0.85 | PLK1 (0.78) | ABL1BCRPRKCACAMK2DSRC | |
| SCHEMBL4902223 | 0.84 | ABL1 (0.80) | ABL1BCRPRKCACAMK2DSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12371408-B2 | Aryl hydrocarbon receptor agonists and uses thereof | NEXYS THERAPEUTICS, INC. (US) | 2025-07-29 | — | — | US | disclosed |
| US-12168646-B2 | Aryl hydrocarbon receptor agonists and uses thereof | NEXYS THERAPEUTICS, INC. (US) | 2024-12-17 | — | — | US | disclosed |
| EP-4472953-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | Nexys Therapeutics, Inc. (US) | 2024-12-11 | — | — | EP | disclosed |
| US-20240279185-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | US | disclosed |
| US-20240208913-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | US | disclosed |
| US-20240208913-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | US | disclosed |
| WO-2023150197-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |
| WO-2023150197-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12371408-B2 | Aryl hydrocarbon receptor agonists and uses thereof | AHR, ARNT, NR1H2 | ABL1 3084/4885BCR 1887/4885PRKCA 3564/4885 |
| US-20240279185-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | AHR, ARNT, NR1H2 | ABL1 3084/4885BCR 1887/4885PRKCA 3564/4885 |
| US-12168646-B2 | Aryl hydrocarbon receptor agonists and uses thereof | AHR, ARNT, NR1H2 | ABL1 3084/4885BCR 1887/4885PRKCA 3564/4885 |
| US-20240208913-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | AHR, ARNT, NR1H2 | ABL1 3084/4885BCR 1887/4885PRKCA 3564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.