Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | UBE2M | P61081 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.33 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.33 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29132505 | 0.93 | HTR2A (0.38) | MC4RHTR2A | |
| SCHEMBL25339129 | 0.90 | MC4R (0.37) | MC4RTRPM8S1PR5MEN1NPC1 | |
| SCHEMBL25340719 | 0.84 | GHSR (0.34) | MC4RMEN1NPC1RAB9AKMT2A | |
| SCHEMBL29132480 | 0.82 | HTR2A (0.38) | MC4RHTR2ATRPM8 | |
| SCHEMBL29626276 | 0.82 | HTR2A (0.38) | MC4RHTR2ATRPM8 | |
| SCHEMBL25340552 | 0.81 | PTPN2 (0.49) | — | |
| SCHEMBL25339199 | 0.78 | PTPN2 (0.43) | HTR2AHTR2CMEN1NPC1RAB9A | |
| SCHEMBL29132471 | 0.78 | RORC (0.35) | HTR2A | |
| SCHEMBL29626362 | 0.77 | HTR2A (0.35) | HTR2AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL25338586 | 0.76 | ITGB3 (0.43) | HTR2AHTR2CS1PR5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4211122-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | Calico Life Sciences LLC (US) | 2023-07-19 | — | — | EP | disclosed |