Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2531921 | 0.94 | NAAA (0.38) | ALDH1A1SMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL2529097 | 0.92 | NAAA (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2ANAAA | |
| SCHEMBL2525641 | 0.92 | NAAA (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2ANAAA | |
| SCHEMBL2529449 | 0.90 | CA1 (0.42) | ALDH1A1ATMCA1NAAATSHR | |
| SCHEMBL1471817 | 0.88 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL6234940 | 0.88 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL2531264 | 0.88 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2ACA1 | |
| SCHEMBL14457774 | 0.88 | NAAA (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2ANAAA | |
| SCHEMBL7224695 | 0.86 | NAAA (0.50) | ALDH1A1ATMCA1NAAATSHR | |
| SCHEMBL2530893 | 0.85 | CA1 (0.41) | ALDH1A1ATMCA1NAAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |