SCHEMBL25337677

SCHEMBL25337677

COc1cccc2cccc(CCCC(F)(F)F)c12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.41
PTGS2 P35354 1/20 0.41
KDM4E B2RXH2 2/20 0.39
GAA P10253 1/20 0.39
RECQL P46063 1/20 0.39
PPARA Q07869 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
ELANE P08246 1/20 0.36
NR3C1 P04150 1/20 0.36
NR3C2 P08235 1/20 0.36
HTR2A P28223 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
KCNA5 P22460 1/20 0.34
HTR6 P50406 1/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
KMT2A Q03164 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PPARG P37231 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25338240 0.79 KCNA5 (0.44) KDM4EELANESMN1; SMN2KCNA5MEN1
SCHEMBL29443540 0.79 KCNA5 (0.44) KDM4EELANESMN1; SMN2KCNA5MEN1
SCHEMBL25336232 0.77 KDM4E (0.43) KDM4EELANENR3C1SMN1; SMN2LMNA
SCHEMBL8974349 0.77 ALOX5 (0.47) ALOX5PTGS2KDM4EGAARECQL
SCHEMBL25338338 0.76 HTR2A (0.53) PPARAHTR2AMEN1KMT2APPARG
SCHEMBL25338671 0.76 ELANE (0.43) KDM4EELANELMNAKMT2AL3MBTL1
SCHEMBL31331867 0.76 KDM4E (0.43) ALOX5PTGS2KDM4EGAARECQL
SCHEMBL27366567 0.76 KDM4E (0.43) ALOX5PTGS2KDM4EGAARECQL
SCHEMBL25337651 0.75 CYP1A2 (0.36) L3MBTL1
SCHEMBL22967810 0.73 KDM4E (0.50) ALOX5PTGS2KDM4EGAARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240032541-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2024-02-01 US disclosed
EP-4210489-A1 HERBICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2023-07-19 EP disclosed
WO-2022053422-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-03-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240032541-A1 HERBICIDAL COMPOUNDS HAX1, DDT, MTX1 ALOX5 2263/4885PTGS2 2197/4885KDM4E 1954/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.