SCHEMBL27366567

SCHEMBL27366567

COc1cccc2cccc(CCO)c12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.43
GAA P10253 1/20 0.43
RECQL P46063 1/20 0.43
ALOX5 P09917 1/20 0.42
PTGS2 P35354 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
PPARG P37231 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
RXRA P19793 1/20 0.41
PPARD Q03181 1/20 0.41
PPARA Q07869 1/20 0.41
HTR2A P28223 2/20 0.40
LMNA P02545 2/20 0.40
IDO1 P14902 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ALDH1A1 P00352 2/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2B Q13224 1/20 0.38
CYP3A4 P08684 2/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31331867 1.00 KDM4E (0.43) KDM4EGAARECQLALOX5PTGS2
SCHEMBL8974349 0.84 ALOX5 (0.47) KDM4EGAARECQLALOX5PTGS2
SCHEMBL10339351 0.80 HTR2A (0.46) PPARGL3MBTL1HTR2AALDH1A1CYP3A4
SCHEMBL22967810 0.79 KDM4E (0.50) KDM4EGAARECQLALOX5PTGS2
SCHEMBL31331965 0.79 HTR2A (0.61) HTR2AHTR6
SCHEMBL27365914 0.79 HTR2A (0.61) HTR2AHTR6
SCHEMBL852646 0.79 TAAR1 (0.64) GAATAAR1LMNAIDO1SMN1; SMN2
SCHEMBL29474956 0.79 TAAR1 (0.64) GAATAAR1LMNAIDO1SMN1; SMN2
SCHEMBL2313474 0.78 ALDH1A1 (0.46) PPARGL3MBTL1HTR2AALDH1A1CYP3A4
SCHEMBL506887 0.78 ALOX5 (0.45) KDM4EALOX5PTGS2TAAR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333371-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-10-30 US disclosed
EP-4532462-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-04-09 EP disclosed
WO-2023230649-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-12-07 WO disclosed
WO-2023230649-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-12-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333371-A1 COMPOUNDS SDHA, PYGB, SLC18A2 KDM4E 3806/4885GAA 302/4885RECQL 941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.