Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR142 | Q7Z601 | 6/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 5/20 | 0.32 |
| ▸ | CTSD | P07339 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25339990 | 0.88 | GPR142 (0.36) | GPR142KCNH2CYP2D6CYP2C9CYP3A4 | |
| SCHEMBL30544079 | 0.88 | GPR142 (0.36) | GPR142KCNH2CYP2D6CYP2C9CYP3A4 | |
| SCHEMBL25340004 | 0.83 | PDE10A (0.40) | GPR142KCNH2CYP2D6CYP2C9CYP3A4 | |
| SCHEMBL25955589 | 0.83 | ATM (0.39) | KCNH2SCN1ASCN4ASCN5ASCN9A | |
| SCHEMBL25341998 | 0.81 | BACE1 (0.43) | BACE1CTSDCTSB | |
| SCHEMBL25955585 | 0.79 | GPR142 (0.34) | GPR142KCNH2CYP2D6CYP2C9CYP3A4 | |
| SCHEMBL30543994 | 0.74 | SCN9A (0.35) | GPR142KCNH2CYP2D6CYP2C9CYP3A4 | |
| SCHEMBL25340424 | 0.74 | SCN9A (0.35) | GPR142KCNH2CYP2D6CYP2C9CYP3A4 | |
| SCHEMBL25952094 | 0.73 | PDE10A (0.40) | KCNH2SCN1ASCN4ASCN5ASCN9A | |
| SCHEMBL25374988 | 0.72 | ADORA2A (0.44) | KCNH2DRD1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |