Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR142 | Q7Z601 | 6/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 6/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 6/20 | 0.33 |
| ▸ | ITGAL | P20701 | 6/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25339990 | 1.00 | GPR142 (0.36) | GPR142CYP2D6CYP2C9KCNH2CYP3A4 | |
| SCHEMBL25338102 | 0.88 | GPR142 (0.37) | GPR142CYP2D6CYP2C9KCNH2CYP3A4 | |
| SCHEMBL30543994 | 0.83 | SCN9A (0.35) | GPR142CYP2D6CYP2C9KCNH2CYP3A4 | |
| SCHEMBL25340424 | 0.83 | SCN9A (0.35) | GPR142CYP2D6CYP2C9KCNH2CYP3A4 | |
| SCHEMBL25955573 | 0.78 | ITGB2 (0.33) | GPR142CYP2D6CYP2C9KCNH2CYP3A4 | |
| SCHEMBL25340004 | 0.74 | PDE10A (0.40) | GPR142CYP2D6CYP2C9KCNH2CYP3A4 | |
| SCHEMBL30544147 | 0.74 | CYP1A2 (0.33) | CYP2D6CYP2C9CYP3A4CYP1A2GAA | |
| SCHEMBL25340911 | 0.74 | CYP1A2 (0.33) | CYP2D6CYP2C9CYP3A4CYP1A2GAA | |
| SCHEMBL30544122 | 0.71 | TRPV1 (0.37) | CYP2D6CYP2C9CYP3A4CYP1A2GAA | |
| SCHEMBL25954052 | 0.71 | TRPV1 (0.37) | CYP2D6CYP2C9CYP3A4CYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |