Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31291153 | 0.87 | GPR119 (0.43) | KMT2ARAB9AMEN1ALDH1A1NPC1 | |
| SCHEMBL30543788 | 0.87 | GPR119 (0.43) | KMT2ARAB9AMEN1ALDH1A1NPC1 | |
| SCHEMBL30543811 | 0.80 | GPR119 (0.45) | KMT2ARAB9AMEN1 | |
| SCHEMBL25338809 | 0.80 | GPR119 (0.45) | KMT2ARAB9AMEN1 | |
| SCHEMBL22750423 | 0.76 | OPRD1 (0.43) | KMT2AMEN1ALDH1A1GAAFPR2 | |
| SCHEMBL25339440 | 0.76 | GAA (0.42) | KMT2ARAB9AMEN1ATMNPC1 | |
| SCHEMBL25340912 | 0.73 | MEN1 (0.44) | KMT2AMEN1ALDH1A1EPHX1MAPT | |
| SCHEMBL25431937 | 0.73 | IL2RA (0.38) | KMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL25429523 | 0.71 | GAA (0.38) | KMT2ARAB9AMEN1ALDH1A1NPC1 | |
| SCHEMBL762459 | 0.70 | RAB9A (0.50) | KMT2ARAB9AMEN1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146785-A1 | PYRROLIDINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2023-08-03 | — | — | WO | disclosed |