Sugi Predict

Sugi Predict / Compounds / SCHEMBL25340243

SCHEMBL25340243

SCHEMBL25340243

O=C1c2ccccc2NC1C1C(=O)N(CO)c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ IDO1 P14902 1/20 0.40
▸ CDC25A P30304 1/20 0.35
▸ ALDH1A1 P00352 5/20 0.34
▸ KDM4E B2RXH2 2/20 0.34
▸ HPGD P15428 2/20 0.34
▸ HDAC3 O15379 2/20 0.33
▸ HDAC4 P56524 2/20 0.33
▸ HDAC1 Q13547 2/20 0.33
▸ HDAC7 Q8WUI4 2/20 0.33
▸ HDAC2 Q92769 2/20 0.33
▸ HDAC10 Q969S8 2/20 0.33
▸ HDAC11 Q96DB2 2/20 0.33
▸ HDAC8 Q9BY41 2/20 0.33
▸ HDAC6 Q9UBN7 2/20 0.33
▸ HDAC9 Q9UKV0 2/20 0.33
▸ HDAC5 Q9UQL6 2/20 0.33
▸ HSD17B10 Q99714 2/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ PDE6D O43924 5/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25342076 0.87 IDO1 (0.37) IDO1CDC25AALDH1A1KDM4EHPGD
SCHEMBL25340158 0.82 IDO1 (0.35) IDO1CDC25AALDH1A1KDM4EPDE6D
SCHEMBL25339922 0.82 CCNB2 (0.37) IDO1CDC25AALDH1A1KDM4EHPGD
SCHEMBL25337338 0.82 ALDH1A1 (0.39) IDO1CDC25AALDH1A1KDM4EHPGD
SCHEMBL25340808 0.82 ALDH1A1 (0.36) IDO1CDC25AALDH1A1KDM4EHPGD
SCHEMBL25339554 0.80 IDO1 (0.41) IDO1CDC25AALDH1A1KDM4EHPGD
SCHEMBL25339867 0.79 ALDH1A1 (0.49) ALDH1A1MEN1KMT2ATSHRLMNA
Hydrochloric Acid SCHEMBL25340490 0.78 ALDH1A1 (0.48) ALDH1A1MEN1KMT2ATSHRLMNA
SCHEMBL25339644 0.78 GAA (0.43) IDO1ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL25342343 0.74 TERT (0.40) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12516022-B2 Derivatives of aryl hydrocarbon receptor agonists AZORA THERAPEUTICS, INC. (US) 2026-01-06 — — US disclosed
US-20240182416-A1 DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS AZORA THERAPEUTICS, INC. 2024-06-06 — — US disclosed
US-11834412-B2 Derivatives of aryl hydrocarbon receptor agonists AZORA THERAPEUTICS, INC. (US) 2023-12-05 — — US disclosed
US-20230227408-A1 DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS AZORA THERAPEUTICS, INC. 2023-07-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227408-A1 DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS AHR, ARNT, NR4A1 IDO1 827/4885CDC25A 4754/4885ALDH1A1 750/4885
US-11834412-B2 Derivatives of aryl hydrocarbon receptor agonists AHR, ARNT, NR4A1 IDO1 827/4885CDC25A 4754/4885ALDH1A1 750/4885
US-20240182416-A1 DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS AHR, ARNT, NR4A1 IDO1 827/4885CDC25A 4754/4885ALDH1A1 750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.