Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | YAP1 | P46937 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | EED | O75530 | 1/20 | 0.37 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.37 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.37 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.37 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30543839 | 1.00 | DPP4 (0.45) | DPP4GPR119MEN1KMT2AMMP13 | |
| SCHEMBL31346176 | 0.88 | GPR119 (0.50) | DPP4GPR119MMP13JAK2JAK1 | |
| SCHEMBL30543841 | 0.88 | DPP4 (0.45) | DPP4GPR119MEN1KMT2AMMP13 | |
| SCHEMBL25339963 | 0.88 | DPP4 (0.45) | DPP4GPR119MEN1KMT2AMMP13 | |
| SCHEMBL25959276 | 0.86 | GPR119 (0.50) | DPP4GPR119MMP13JAK2JAK1 | |
| SCHEMBL25339356 | 0.85 | USP30 (0.44) | DPP4GPR119MEN1KMT2AMMP13 | |
| SCHEMBL31599068 | 0.82 | DPP4 (0.48) | DPP4GPR119MEN1KMT2AMMP13 | |
| SCHEMBL31346185 | 0.82 | GPR119 (0.54) | DPP4GPR119MMP13JAK2JAK1 | |
| SCHEMBL31291143 | 0.82 | DPP4 (0.43) | DPP4GPR119MEN1KMT2AMMP13 | |
| SCHEMBL30543935 | 0.82 | DPP4 (0.43) | DPP4GPR119MEN1KMT2AMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146785-A1 | PYRROLIDINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2023-08-03 | — | — | WO | disclosed |