Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MYC | P01106 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 3/20 | 0.32 |
| ▸ | TDO2 | P48775 | 2/20 | 0.32 |
| ▸ | MAX | P61244 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30520827 | 1.00 | POLB (0.37) | POLBMYCALDH1A1DRD2NPC1 | |
| SCHEMBL30520743 | 0.90 | POLB (0.36) | POLBMYCALDH1A1DRD2IDO1 | |
| SCHEMBL25342122 | 0.90 | POLB (0.36) | POLBMYCALDH1A1DRD2IDO1 | |
| SCHEMBL31053925 | 0.89 | POLB (0.44) | POLBMYCALDH1A1DRD2IDO1 | |
| SCHEMBL30521537 | 0.84 | ALDH1A1 (0.37) | POLBMYCALDH1A1DRD2IDO1 | |
| SCHEMBL25342588 | 0.84 | ALDH1A1 (0.37) | POLBMYCALDH1A1DRD2IDO1 | |
| SCHEMBL25342611 | 0.83 | POLB (0.33) | POLBMYCNPC1IDO1TDO2 | |
| SCHEMBL30521090 | 0.83 | POLB (0.33) | POLBMYCNPC1IDO1TDO2 | |
| SCHEMBL25342753 | 0.83 | ACHE (0.37) | POLBMYCALDH1A1DRD2IDO1 | |
| SCHEMBL30521077 | 0.83 | ACHE (0.37) | POLBMYCALDH1A1DRD2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143494-A1 | NEW PROTAC COMPOUND | 甘李药业股份有限公司 | 2023-08-03 | — | — | WO | disclosed |