Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 3/20 | 0.31 |
| ▸ | TDO2 | P48775 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25342753 | 1.00 | ACHE (0.37) | ACHEPOLBHTR4FAAHKCNH2 | |
| SCHEMBL30521537 | 0.92 | ALDH1A1 (0.37) | ACHEPOLBKCNH2GSTP1GSTM2 | |
| SCHEMBL25342588 | 0.92 | ALDH1A1 (0.37) | ACHEPOLBKCNH2GSTP1GSTM2 | |
| SCHEMBL30521235 | 0.89 | ACHE (0.34) | ACHEPOLBFAAHKCNH2GSTP1 | |
| SCHEMBL25343824 | 0.89 | ACHE (0.34) | ACHEPOLBFAAHKCNH2GSTP1 | |
| SCHEMBL31053925 | 0.87 | POLB (0.44) | POLBMYCALDH1A1IDO1TDO2 | |
| SCHEMBL25342611 | 0.85 | POLB (0.33) | ACHEPOLBMYCIDO1TDO2 | |
| SCHEMBL30521090 | 0.85 | POLB (0.33) | ACHEPOLBMYCIDO1TDO2 | |
| SCHEMBL25342017 | 0.83 | POLB (0.37) | POLBMYCALDH1A1IDO1TDO2 | |
| SCHEMBL30520827 | 0.83 | POLB (0.37) | POLBMYCALDH1A1IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118574822-A | Novel PROTAC compounds | 甘李药业股份有限公司 | 2024-08-30 | — | — | CN | disclosed |
| WO-2023143494-A1 | NEW PROTAC COMPOUND | 甘李药业股份有限公司 | 2023-08-03 | — | — | WO | disclosed |