Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.48 |
| ▸ | CYCS | P99999 | 3/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4268982 | 0.85 | STAT3 (0.55) | TOP1CYCSAKR1B1TDP1GRIN2D | |
| Hydrochloric Acid SCHEMBL8865689 | 0.85 | TOP1 (0.42) | TOP1CYCSENPP2 | |
| SCHEMBL8865552 | 0.81 | TSHR (0.43) | TOP1CYCS | |
| SCHEMBL9371085 | 0.79 | TERT (0.40) | TOP1CYCSENPP2 | |
| SCHEMBL1639280 | 0.79 | TOP1 (0.50) | TOP1CYCSENPP2 | |
| SCHEMBL29660266 | 0.78 | TOP1 (0.55) | TOP1CYCSENPP2 | |
| SCHEMBL935287 | 0.78 | TOP1 (0.55) | TOP1CYCSENPP2 | |
| SCHEMBL14936110 | 0.77 | TOP1 (0.54) | TOP1CYCSENPP2 | |
| SCHEMBL28507859 | 0.77 | TOP1 (0.54) | TOP1CYCSENPP2 | |
| SCHEMBL30925043 | 0.77 | TOP1 (0.54) | TOP1CYCSENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670217-B2 | Process for preparing chlorins and their pharmaceutical uses | UNIVERSIDADE DE COIMBRA (PT) | 2017-06-06 | — | — | US | disclosed |
| CN-102227432-B | Process for preparing chlorins and their pharmaceutical uses | UNIV DE COIMBRA | 2015-04-22 | — | — | CN | disclosed |
| EP-2346874-B1 | PROCESS FOR PREPARING CHLORINS AND THEIR PHARMACEUTICAL USES | UNIV DE COIMBRA (PT) | 2013-12-04 | — | — | EP | disclosed |
| US-20110250143-A1 | PROCESS FOR PREPARING CHLORINS AND THEIR PHARMACEUTICAL USES | UNIVERSIDADE DE COIMBRA (PT) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110250143-A1 | PROCESS FOR PREPARING CHLORINS AND THEIR PHARMACEUTICAL USES | CD68, HMBS, MKI67 | TOP1 1814/4885CYCS 1438/4885AKR1B1 2630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.