SCHEMBL4268982 — predicted protein targets

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	STAT3	P40763	1/20	0.55

▸	STAT1	P42224	1/20	0.55

▸	PPARG	P37231	1/20	0.36

▸	FFAR1	O14842	2/20	0.35

▸	TOP1	P11387	3/20	0.35

▸	CYCS	P99999	3/20	0.34

▸	AKR1B1	P15121	1/20	0.34

▸	TDP1	Q9NUW8	1/20	0.34

▸	GRIN2D	O15399	1/20	0.33

▸	GRIN3B	O60391	1/20	0.33

▸	GRIN1	Q05586	1/20	0.33

▸	GRIN2A	Q12879	1/20	0.33

▸	GRIN2B	Q13224	1/20	0.33

▸	GRIN2C	Q14957	1/20	0.33

▸	GRIN3A	Q8TCU5	1/20	0.33

▸	PTGDR2	Q9Y5Y4	1/20	0.33

▸	PTGER1	P34995	1/20	0.33

▸	PTGER4	P35408	1/20	0.33

▸	PTGER3	P43115	1/20	0.33

▸	PTGER2	P43116	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2534332	0.85	TOP1 (0.48)	PPARGFFAR1TOP1CYCSAKR1B1
SCHEMBL4268682	0.83	STAT3 (0.54)	STAT3STAT1
SCHEMBL27827077	0.81	STAT3 (0.37)	STAT3STAT1PPARGFFAR1AKR1B1
SCHEMBL1998702	0.80	STAT3 (0.56)	STAT3STAT1TOP1CYCSKDM4E
SCHEMBL30583768	0.79	STAT3 (0.55)	STAT3STAT1TOP1CYCSKDM4E
SCHEMBL30583773	0.79	STAT3 (0.55)	STAT3STAT1TOP1CYCSKDM4E
SCHEMBL29062206	0.79	STAT3 (0.55)	STAT3STAT1TOP1CYCSKDM4E
SCHEMBL30583769	0.78	STAT3 (0.53)	STAT3STAT1TOP1CYCSKDM4E
SCHEMBL2849607	0.77	STAT3 (0.58)	STAT3STAT1KDM4EMEN1ALDH1A1
SCHEMBL8689812	0.76	STAT3 (0.60)	STAT3STAT1FFAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7521551-B2	Chlorins possessing fused ring systems useful as photoselective compounds for photodynamic therapy	MIRAVANT PHARMACEUTICALS, INC. (US)	2009-04-21	—	—	US	disclosed
US-20080275232-A1	CHLORINS POSSESSING FUSED RING SYSTEMS USEFUL AS PHOTOSELECTIVE COMPOUNDS FOR PHOTODYNAMIC THERAPY	MIRAVANT PHARMACEUTICALS, INC.	2008-11-06	—	—	US	disclosed
US-20050020560-A1	Chlorins processing fused ring systems useful as photoselective compounds for photodynamic therapy	MIRAVANT PHARMACEUTICALS, INC.	2005-01-27	—	—	US	disclosed
US-6794505-B1	Chlorins possessing fused ring systems useful as photoselective compounds for photodynamic therapy	MIRAVANT PHARMACEUTICALS, INC.	2004-09-21	—	—	US	disclosed
WO-2001074818-A1	CHLORINS WITH FUSED RINGS FOR USE IN PHOTODYNAMIC THERAPY	MIRAVANT PHARMACEUTICALS, INC. (US)	2001-10-11	—	—	WO	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20080275232-A1	CHLORINS POSSESSING FUSED RING SYSTEMS USEFUL AS PHOTOSELECTIVE COMPOUNDS FOR PHOTODYNAMIC THERAPY	PPOX, HMBS, DDT	STAT3 3696/4885STAT1 3561/4885PPARG 1165/4885
US-20050020560-A1	Chlorins processing fused ring systems useful as photoselective compounds for photodynamic therapy	PPOX, HMBS, DDT	STAT3 3916/4885STAT1 3672/4885PPARG 1417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.