SCHEMBL253444

SCHEMBL253444

Cc1cccc(Cl)c1Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.45
CALM1 P0DP23 1/20 0.42
LMNA P02545 2/20 0.40
TYMP P19971 1/20 0.40
AKR1B1 P15121 1/20 0.39
NR1H2 P55055 1/20 0.39
NR1H3 Q13133 1/20 0.39
ATM Q13315 1/20 0.38
MEN1 O00255 1/20 0.38
CYP3A4 P08684 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
KMT2A Q03164 1/20 0.38
HIF1A Q16665 1/20 0.38
HSD17B10 Q99714 1/20 0.38
OPRM1 P35372 1/20 0.38
OPRD1 P41143 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5247984 0.85 CALM1 (0.52) CALM1LMNATYMPAKR1B1NR1H2
SCHEMBL7918609 0.85 CALM1 (0.52) IDH1CALM1CYP3A4HPGDTAAR1
SCHEMBL10798580 0.80 SMN1; SMN2 (0.47) LMNAMEN1KMT2ATAAR1
SCHEMBL29532678 0.79 IDH1 (0.47) IDH1CALM1MEN1CYP3A4HPGD
SCHEMBL9719201 0.79 IDH1 (0.47) IDH1CALM1MEN1CYP3A4HPGD
SCHEMBL146769 0.79 IDH1 (0.47) IDH1CALM1MEN1CYP3A4HPGD
SCHEMBL10923606 0.78 CALM1 (0.41) IDH1CALM1TYMPNR1H2NR1H3
SCHEMBL27292305 0.78 CALM1 (0.41) IDH1CALM1LMNATYMPNR1H2
SCHEMBL16933813 0.78 IDH1 (0.44) IDH1CALM1TYMPNR1H2NR1H3
Ammonia Solution, Strong SCHEMBL7793996 0.77 CALM1 (0.39) IDH1CALM1LMNATYMPNR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4139137-A None JP disclosed
EP-3527600-B1 ISOCYANATE COMPOSITION AND PRODUCTION METHOD FOR ISOCYANATE POLYMER ASAHI CHEMICAL IND (JP) 2025-07-09 EP disclosed
US-20250188004-A1 INTEGRATED NAPHTHA REFORMING AND BENZYL TOLUENE PRODUCTION PROCESS SAUDI ARABIAN OIL COMPANY (SA) 2025-06-12 US disclosed
US-20230114799-A1 ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-04-13 US disclosed
US-11548975-B2 Isocyanate composition and method for producing isocyanate polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-01-10 US disclosed
CN-109803992-B Isocyanate composition and method for producing isocyanate polymer 旭化成株式会社 2022-05-24 CN disclosed
CN-109843963-B Isocyanate composition, method for producing isocyanate polymer, and isocyanate polymer 旭化成株式会社 2022-05-13 CN disclosed
EP-3536683-B1 POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION ASAHI CHEMICAL IND (JP) 2021-11-24 EP disclosed
US-11174337-B2 Isocyanate composition, method for producing isocyanate polymer and isocyanate polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-11-16 US disclosed
CN-107963982-B Polyisocyanate composition and isocyanate polymer composition 旭化成株式会社 2021-11-12 CN disclosed
EP-0306398-B1 CHEMICAL PROCESS FOR THE DESTRUCTION OF HALOGENATED ORGANIC PRODUCTS ELF ATOCHEM S.A. (FR) 1993-02-03 EP disclosed
JP-H04139137-A SYNTHESIS OF BENZYLTOLUENE AND DIBENZYLTOLUENE HAVING LOW CHLORINE CONTENT SOC ATOCHEM 1992-05-13 JP disclosed
CN-1052845-A The benzyl toluene of low chlorine content and the synthetic method of dibenzyl toluene AUTOCHEM (FR) 1991-07-10 CN disclosed
EP-0435737-A1 Process for the synthesis of benzyltoluene and dibenzyltoluene with low chlorine content ELF ATOCHEM S.A. (FR) 1991-07-03 EP disclosed
CN-1011696-B Substantially non-flammable, biodegradable functional liquids HYDROCOR FORSCH ANALYTIK (DE) 1991-02-20 CN disclosed
EP-0306398-A1 Chemical process for the destruction of halogenated organic products ELF ATOCHEM S.A. (FR) 1989-03-08 EP disclosed
CN-85101151-A Non-flammable in fact, biodegradable functional liquid 1987-02-18 CN disclosed
EP-0070218-B1 HALOGENATED AROMATIC COMPOUNDS SUITABLE AS FIRE RETARDERS ELF ATOCHEM S.A. (FR) 1985-06-19 EP disclosed
US-4117019-A MANUFACTURE OF O-BENZYLTOLUENES BASF AKTIENGESELLSCHAFT (DE) 1978-09-26 US disclosed
US-3978144-A MANUFACTURE OF O-BENZYLTOLUENES BASF AKTIENGESELLSCHAFT (DT) 1976-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11548975-B2 Isocyanate composition and method for producing isocyanate polymer IDH3A, IDH2, IDH3B IDH1 4/4885CALM1 2533/4885LMNA 2021/4885
US-20230114799-A1 ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER IDH3A, IDH2, IDH3B IDH1 4/4885CALM1 2533/4885LMNA 1933/4885
US-20250188004-A1 INTEGRATED NAPHTHA REFORMING AND BENZYL TOLUENE PRODUCTION PROCESS FLI1, LIPA, TCF4 IDH1 886/4885CALM1 2069/4885LMNA 1125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.